Track‐etched nanopore/membrane: from fundamental to applications

T Ma, JM Janot, S Balme - Small Methods, 2020 - Wiley Online Library
Biomimetic and bio‐inspired membranes draw great attention and generate extensive efforts
to solve environmental, health, and energy issues. In this field, track‐etched membranes …

A glimpse of structural biology through X-ray crystallography

Y Shi - Cell, 2014 - cell.com
Since determination of the myoglobin structure in 1957, X-ray crystallography, as the
anchoring tool of structural biology, has played an instrumental role in deciphering the …

Phase transition in postsynaptic densities underlies formation of synaptic complexes and synaptic plasticity

M Zeng, Y Shang, Y Araki, T Guo, RL Huganir… - Cell, 2016 - cell.com
Postsynaptic densities (PSDs) are membrane semi-enclosed, submicron protein-enriched
cellular compartments beneath postsynaptic membranes, which constantly exchange their …

PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density

X Chen, JM Levy, A Hou, C Winters… - Proceedings of the …, 2015 - National Acad Sciences
The postsynaptic density (PSD)-95 family of membrane-associated guanylate kinases
(MAGUKs) are major scaffolding proteins at the PSD in glutamatergic excitatory synapses …

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

MD Gomes, SH Lecker, RT Jagoe… - Proceedings of the …, 2001 - National Acad Sciences
Muscle wasting is a debilitating consequence of fasting, inactivity, cancer, and other
systemic diseases that results primarily from accelerated protein degradation by the …

Wnt signaling: a common theme in animal development

KM Cadigan, R Nusse - Genes & development, 1997 - genesdev.cshlp.org
Wnt proteins are now recognized as one of the major families of developmentally important
signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in the …

Mechanisms of Wnt signaling in development

A Wodarz, R Nusse - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract Wnt genes encode a large family of secreted, cysteine-rich proteins that play key
roles as intercellular signaling molecules in development. Genetic studies in Drosophila and …

PDZ domains and their binding partners: structure, specificity, and modification

HJ Lee, JJ Zheng - Cell communication and Signaling, 2010 - Springer
PDZ domains are abundant protein interaction modules that often recognize short amino
acid motifs at the C-termini of target proteins. They regulate multiple biological processes …

PDZ domain proteins of synapses

E Kim, M Sheng - Nature Reviews Neuroscience, 2004 - nature.com
PDZ domains are protein-interaction domains that are often found in multi-domain
scaffolding proteins. PDZ-containing scaffolds assemble specific proteins into large …

Evolutionarily conserved pathways of energetic connectivity in protein families

SW Lockless, R Ranganathan - Science, 1999 - science.org
For mapping energetic interactions in proteins, a technique was developed that uses
evolutionary data for a protein family to measure statistical interactions between amino acid …