The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants

KF Zahra, R Lefter, A Ali, EC Abdellah… - Oxidative Medicine …, 2021 - Wiley Online Library
Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

[HTML][HTML] Redox control of cancer cell destruction

C Hegedűs, K Kovács, Z Polgár, Z Regdon, É Szabó… - Redox biology, 2018 - Elsevier
Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …

Microenvironmental reactive oxygen species in colorectal cancer: involved processes and therapeutic opportunities

MA Sorolla, I Hidalgo, A Sorolla, R Montal, O Pallisé… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is a disease associated with a high mortality rate. During
the tumorigenic process, several factors and signaling molecules produced by tumor cells …

New challenges to study heterogeneity in cancer redox metabolism

R Benfeitas, M Uhlen, J Nielsen… - Frontiers in cell and …, 2017 - frontiersin.org
Reactive oxygen species (ROS) are important pathophysiological molecules involved in vital
cellular processes. They are extremely harmful at high concentrations because they promote …

Silk fibroin peptide suppresses proliferation and induces apoptosis and cell cycle arrest in human lung cancer cells

M Wang, Y Du, H Huang, Z Zhu, S Du, S Chen… - Acta Pharmacologica …, 2019 - nature.com
Silkworm cocoon was recorded to cure carbuncle in the Compendium of Materia Medica.
Previous studies have demonstrated that the supplemental silk protein sericin exhibits …

Exploring Therapeutic Potential of Catalase: Strategies in Disease Prevention and Management

S Anwar, F Alrumaihi, T Sarwar, AY Babiker, AA Khan… - Biomolecules, 2024 - mdpi.com
The antioxidant defense mechanisms play a critical role in mitigating the deleterious effects
of reactive oxygen species (ROS). Catalase stands out as a paramount enzymatic …

Molecular changes during acute myeloid leukemia (AML) evolution and identification of novel treatment strategies through molecular stratification

E Karjalainen, GA Repasky - … in molecular biology and translational science, 2016 - Elsevier
Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by impaired
differentiation and uncontrollable proliferation of myeloid progenitor cells. Due to high …

Synthesis of polyphosphazene and preparation of microspheres from polyphosphazene blends with PMMA for drug combination therapy

RS Ullah, L Wang, H Yu, M Haroon… - Journal of materials …, 2019 - Springer
Drug combination therapy is an emerging technology to treat the diseases which are still
annoyance to human being. Combination of two or more drugs can deal with diseases in a …

Comparison of tumor related signaling pathways with known compounds to determine potential agents for lung adenocarcinoma

S Xu, R Liu, Y Da - Thoracic Cancer, 2018 - Wiley Online Library
Background This study compared tumor‐related signaling pathways with known compounds
to determine potential agents for lung adenocarcinoma (LUAD) treatment. Methods Kyoto …

[PDF][PDF] Antioxidant enzymes level detection in cisplatin treated iraqi lung cancer patients and in vitro estimating the cytotoxic and reactive oxygen species generation in …

F Hassan, AZ Al-Saffar, AF Al-Shanon - Int. J. Pharm. Qual. Assur, 2020 - researchgate.net
Cisplatin is one of the most important and effective antitumor drug used as treatment against
different types of tumors. Cisplatin directly affects DNA integrity as well as the generation of …