Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most popular
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …

Most drugs used daily are chiral compounds and exist in the form of racemic mixtures, so the
separation of enantiomers has always been concerned because of their similar chemical …

The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

Chirality is a common phenomenon in nature. Different enantiomers of chiral drug
compounds have obvious differences in their effects on the human body. Therefore, the …

Method screening is an integral part of chromatographic method development for the
separation of racemates. Due to the highly complex retention mechanism of a chiral …

Stereoselective chiral molecules are responsible for specific biological functions in nature.
At present, more than half of the prescribed drugs are chiral. Living organisms display …

Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and
food additives are being commercialized as racemic mixtures, although in most cases only …

Chiral metal-organic frameworks (CMOFs) have been explored as potential chiral stationary
phases (CSPs) for chiral high performance liquid chromatography (HPLC). However, their …

Abstract α-Amino acids are present in two opposite configurations due to the presence of a
central carbon atom which is a chiral center. While l-amino acids are present in large …

Application of the superficially porous particles (SPPs) grafted with chiral selectors can
substantially improve resolution in chromatographic techniques. In this work, we carried out …