Iron and copper in male reproduction: a double-edged sword

E Tvrda, R Peer, SC Sikka, A Agarwal - Journal of assisted reproduction …, 2015 - Springer
Iron and copper are essential trace nutrients playing important roles in general health and
fertility. However, both elements are highly toxic when accumulating in large quantities …

Sperm DNA tests as useful adjuncts to semen analysis

SEM Lewis, I Agbaje, J Alvarez - Systems biology in reproductive …, 2008 - Taylor & Francis
Male infertility has traditionally been diagnosed by microscopic assessment of
concentration, motility and morphology of sperm in the ejaculate. Most laboratories use …

Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay

D Evenson, R Wixon - Reproductive biomedicine online, 2006 - Elsevier
Meta-analyses were conducted to investigate the relationship of sperm DNA fragmentation
on pregnancy outcome using in-vivo fertilization, IUI, routine IVF and ICSI. Couples with no …

PM2. 5 caused ferroptosis in spermatocyte via overloading iron and disrupting redox homeostasis

J Wang, Z Zhang, F Shi, Y Li, Y Tang, C Liu… - Science of The Total …, 2023 - Elsevier
Abstract Fine particulate matter (PM 2.5) has been reported to cause various types of
damage to male reproductive system, but the research on the underlying mechanisms is still …

Pregnancy in women with thalassemia: challenges and solutions

G Petrakos, P Andriopoulos… - International journal of …, 2016 - Taylor & Francis
Advances in treatment of thalassemia have led to the aging of thalassemic patients, and
consequently concern about successful reproductive outcome is augmented. Although …

Effects of environmental and pathological hypoxia on male fertility

Z Li, S Wang, C Gong, Y Hu, J Liu, W Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Male infertility is a widespread health problem affecting approximately 6%–8% of the male
population, and hypoxia may be a causative factor. In mammals, two types of hypoxia are …

[HTML][HTML] Gender-related variations in iron metabolism and liver diseases

DD Harrison-Findik - World journal of hepatology, 2010 - ncbi.nlm.nih.gov
The regulation of iron metabolism involves multiple organs including the duodenum, liver
and bone marrow. The recent discoveries of novel iron-regulatory proteins have brought the …

The association between iron, calcium, and oxidative stress in seminal plasma and sperm quality

O Ammar, Z Houas, M Mehdi - Environmental science and pollution …, 2019 - Springer
The present study aimed to determine the level of iron and calcium in the seminal plasma of
men with different fertility potentials and to examine its relationship with oxidative stress …

Osteoporosis syndrome in thalassaemia major: an overview

M Toumba, N Skordis - Journal of osteoporosis, 2010 - Wiley Online Library
Osteoporosis in thalassaemia major (TM) represents a prominent cause of morbidity. The
mechanism of pathogenesis of bone disease (BD) in TM is multifactorial and complicated …

Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes

SEM Lewis, IM Agbaje - Mutagenesis, 2008 - academic.oup.com
Infertility affects one in six couples in Europe during their reproductive years with
dysfunctional sperm being one of the most common causes. Conventional semen analysis …