Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal
dysfunction and degeneration. As glutamate is a major excitatory neurotransmitter in the …

✓ In patients with spinal cord injury, the primary or mechanical trauma seldom causes total
transection, even though the functional loss may be complete. In addition, biochemical and …

We have evaluated the use of 2, 3, 5-triphenyltetrazolium chloride (TTC) as an
histopathologic stain for identification of infarcted rat brain tissue. The middle cerebral artery …

Rats were implanted with 0.3‐mm‐diameter dialysis tubing through the hippocampus and
subsequently perfused with Ringer's solution at a flow rate of 2 (μ1/min. Samples of the …

We have tested whether small intraischemic variations in brain temperature influence the
outcome of transient ischemia. To measure brain temperature, a thermocouple probe was …

Selective vulnerability of the hippocampus in brain ischemia - ScienceDirect Skip to main
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Transient ischemia in animals produces delayed cell death in vulnerable hippocampal
neurons. To see if this occurs in humans, we reexamined brain slides from all patients with …

Epigenetic modifications, including changes in DNA methylation, lead to altered gene
expression and thus may underlie epileptogenesis via induction of permanent changes in …

A rat model of third trimester fetal alcohol exposure was used to determine whether a
smaller daily dose of alcohol can induce more severe microencephaly and neuronal loss …

The aim of this study was to measure extracellular chemical changes in the cerebral cortex
in response to compression contusion trauma in rats. Energy-related metabolites (ie, lactate …