Overcoming resolution attenuation during tilted cryo-EM data collection
Structural biology efforts using cryogenic electron microscopy are frequently stifled by
specimens adopting “preferred orientations” on grids, leading to anisotropic map resolution …
specimens adopting “preferred orientations” on grids, leading to anisotropic map resolution …
Structural basis of branching during RNA splicing
Branching is a critical step in RNA splicing that is essential for 5′ splice site selection.
Recent spliceosome structures have led to competing models for the recognition of the …
Recent spliceosome structures have led to competing models for the recognition of the …
[HTML][HTML] Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding
Integrase (IN) performs dual essential roles during HIV-1 replication. During ingress, IN
functions within an oligomeric “intasome” assembly to catalyze viral DNA integration into …
functions within an oligomeric “intasome” assembly to catalyze viral DNA integration into …
Cryogenic electron microscopy studies on hydrogenases
C Furlan - 2023 - etheses.whiterose.ac.uk
Hydrogenases are enzymes that produce or consume hydrogen (H2). They have central
roles in microbial metabolism and have been of biotechnological interest. In this thesis two …
roles in microbial metabolism and have been of biotechnological interest. In this thesis two …
Characterization of L. pneumophila PurE, B. cenocepacia PurE and MHV68 ORF75C Through a Structural Biology Lens
K Belfon - 2023 - search.proquest.com
Purine biosynthesis is essential to the survival and function of cells in living organisms.
Purines are critical components in our genetic material, our energy source for biochemical …
Purines are critical components in our genetic material, our energy source for biochemical …