Neuronal ensembles are local, sparsely distributed populations of neurons that are reliably
re-activated by a specific stimulus, context or task. Such discrete cell populations can be …

Alcohol use disorder (AUD) continues to be challenging to treat despite the best available
interventions, with two-thirds of individuals going on to relapse by 1 year after treatment …

Major Depressive Disorder (MDD) is a complex, heterogeneous condition affecting millions
worldwide. Computational neuropsychiatry offers potential breakthroughs through the …

Background Brain-based interventions are needed to address persistent relapse in alcohol
use disorder (AUD). Neuroimaging evidence suggests higher frontal connectivity as well as …

Women are drinking alcohol as much as men for the first time in history. Women experience
more health-related consequences from alcohol use disorder (AUD), like increased …

Growing evidence suggests greater vulnerability of women than men to the adverse effects
of alcohol on mood and sleep. However, the underlying neurobiological mechanisms are …

Theoretical models group maladaptive behaviors in addiction into neurocognitive domains
such as incentive salience (IS), negative emotionality (NE), and executive functioning (EF) …

Background The hypothalamus is involved in stress regulation and reward processing, with
its various nuclei exhibiting unique functions and connections. However, human …

Alcohol dependence (AD) is a debilitating disease associated with high relapse rates even
after long periods of abstinence. Thus, elucidating neurobiological substrates of relapse risk …

BRAIN COMMUNICATIONS AIN COMMUNICATIONS Page 1 Diminished preparatory
physiological responses in frontotemporal lobar degeneration syndromes Kuan-Hua Chen,1 Alice …