Discovered in 1987 as a potent endothelial cell–derived vasoconstrictor peptide, endothelin-
1 (ET-1), the predominant member of the endothelin peptide family, is now recognized as a …

The endothelin axis, recognized for its vasoconstrictive action, plays a central role in the
pathology of pulmonary arterial hypertension (PAH). Treatment with approved endothelin …

There is a complex interaction between the brain and the cerebral vasculature to meet the
metabolic demands of the brain for proper function. Preservation of cerebrovascular function …

This study investigated the ameliorative effects of beta-carotene (BC) on diabetes-
associated vascular dementia and its action against biomolecule oxidation. The diabetic …

Dementia in general and Alzheimer's disease in particular is increasingly seen in
association with autoimmunity being causatively or supportively involved in the …

The global epidemic of diabetes is of significant concern. Diabetes associated vascular
disease signifies the principal cause of morbidity and mortality in diabetic patients. It is also …

Diabetes and cognitive dysfunction, ranging from mild cognitive impairment to dementia,
often coexist in individuals over 65 years of age. Vascular contributions to cognitive …

Background: Declined kidney function associated with hypertension is a danger for cognitive
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …

This experiment was aimed to investigate the effect of Dengzhan Shengmai capsule
combined with butylphthalide soft capsule on oxidative stress indexes and serum …

Ischemic stroke is a medical condition that arises because of poor blood supply to the brain.
Reperfusion being salvage to the brain further causes, exacerbation of tissue injury, known …