[PDF][PDF] Ovarian microenvironment: challenges and opportunities in protecting against chemotherapy-associated ovarian damage

Y Guo, L Xue, W Tang, J Xiong, D Chen… - Human …, 2024 - academic.oup.com
BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Oxidative damage as a fundament of systemic toxicities induced by cisplatin—the crucial limitation or potential therapeutic target?

JS Katanić Stanković, D Selaković, G Rosić - International journal of …, 2023 - mdpi.com
Cisplatin, an inorganic complex of platinum, is a chemotherapeutic drug that has been used
for 45 years. Despite the progress of pharmaceutical sciences and medicine and the …

In vivo and In silico evidence of the protective properties of carvacrol against experimentally-induced gastric ulcer: Implication of antioxidant, anti-inflammatory, and …

AM Badr, NF El-Orabi, YF Mahran, AM Badr… - Chemico-Biological …, 2023 - Elsevier
Gastric ulcer is a serious disease that affects millions of individuals worldwide. Alcohol
consumption is a major contributor to the disease pathogenesis and ethanol-induced ulcer …

Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity—a review of literature evidence

AC Famurewa, MY George, CA Ukwubile, S Kumar… - BioMetals, 2024 - Springer
Anticancer chemotherapy (ACT) remains a cornerstone in cancer treatment, despite
significant advances in pharmacology over recent decades. However, its associated side …

Carvacrol showed a curative effect on reproductive toxicity caused by Bisphenol AF via antioxidant, anti-inflammatory and anti-apoptotic properties

A Uyar, M Cellat, Ö Kanat, M Etyemez, T Kutlu… - Reproductive …, 2023 - Elsevier
Bisphenol AF (BPAF) is an endocrine disruptor, and human exposure to these chemicals is
growing in industrialized nations. BPAF has been demonstrated in studies to have toxic …

Effects of carvacrol on hormonal, inflammatory, antioxidant changes, and ovarian reserve in polycystic ovary syndrome in Wistar rats

İ Gökçek, G Uyanık, T Tutar, A Gözer - Naunyn-Schmiedeberg's Archives …, 2024 - Springer
The study, which explored the effects of carvacrol on female reproductive health, particularly
in terms of hormonal, inflammatory, antioxidant, and ovarian reserves in polycystic ovary …

[PDF][PDF] Impact of Carvacrol on Ovarian and Uterine Changes Induced by Hyperthyroidism in Rats

İ GÖKÇEK, M GÜVENÇ - inflammation, 2024 - veteriner.fusabil.org
This study evaluates the effects of carvacrol, used in hyperthyroidism, on ovarian reserve as
well as inflammatory and oxidative stress. In the study, thirty-five female Wistar albino rats …

Carvacrol Ameliorates Cisplatin-Induced Cardiotoxicity By Regulating Notch/Hes1 Signaling Pathway, Oxidative Stress and Cell Death In Rat Cardiac Tissue

N Akaras, Ö Kandemir, H Şimşek - Türk Doğa ve Fen Dergisi, 2024 - dergipark.org.tr
Sisplatin esas olarak katı tümörlerin tedavisinde kullanılan en aktif sitotoksik ajanlardan
biridir. Sisplatin'in yüksek doz ve uzun süreli kullanımı kardiyotoksisiteye neden olduğu …

The effect of Usnea longissima extract on chemotherapy-associated multi-organ damage in rats

E Bingul, B Suleyman, R Mammadov, S Bulut… - 2023 - researchsquare.com
The toxic effects of doxorubicin and cisplatin in various organs have been associated with
oxidative stress. Studies have shown that Usnea longissima has strong antioxidant effects …

[HTML][HTML] Sıçanlarda Hipertiroidizm Kaynaklı Ovaryum ve Uterus Değişiklikleri Üzerine Karvakrolün Etkisi

İ GÖKÇEK, M GÜVENÇ - veteriner.fusabil.org
Özet Hipertiroidizmde kullanılan karvakrolün ovaryum rezervi ile yangısal ve oksidatif stres
üzerine etkilerinin değerlendirildiği bu çalışmada Wistar albino cinsi dişi otuz beş sıçan her …