[HTML][HTML] Current issues in research on structure–property relationships in polymer nanocomposites

J Jancar, JF Douglas, FW Starr, SK Kumar… - Polymer, 2010 - Elsevier
The understanding of the basic physical relationships between nano-scale structural
variables and the macroscale properties of polymer nanocomposites remains in its infancy …

Intermediate filaments: from cell architecture to nanomechanics

H Herrmann, H Bär, L Kreplak, SV Strelkov… - … reviews Molecular cell …, 2007 - nature.com
Intermediate filaments (IFs) constitute a major structural element of animal cells. They build
two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major …

Emergent complexity of the cytoskeleton: from single filaments to tissue

F Huber, J Schnauß, S Rönicke, P Rauch… - Advances in …, 2013 - Taylor & Francis
Despite their overwhelming complexity, living cells display a high degree of internal
mechanical and functional organization which can largely be attributed to the intracellular …

Keratins as the main component for the mechanical integrity of keratinocytes

L Ramms, G Fabris, R Windoffer… - Proceedings of the …, 2013 - National Acad Sciences
Keratins are major components of the epithelial cytoskeleton and are believed to play a vital
role for mechanical integrity at the cellular and tissue level. Keratinocytes as the main cell …

Intermediate filaments control collective migration by restricting traction forces and sustaining cell–cell contacts

C De Pascalis, C Pérez-González… - Journal of cell …, 2018 - rupress.org
Mesenchymal cell migration relies on the coordinated regulation of the actin and
microtubule networks that participate in polarized cell protrusion, adhesion, and contraction …

Deformation and failure of protein materials in physiologically extreme conditions and disease

MJ Buehler, YC Yung - Nature materials, 2009 - nature.com
Biological protein materials feature hierarchical structures that make up a diverse range of
physiological materials. The analysis of protein materials is an emerging field that uses the …

Mechanical response of cytoskeletal networks

ML Gardel, KE Kasza, CP Brangwynne, J Liu… - Methods in cell …, 2008 - Elsevier
The cellular cytoskeleton is a dynamic network of filamentous proteins, consisting of
filamentous actin (F‐actin), microtubules, and intermediate filaments. However, these …

A comparison of the mechanical and structural properties of fibrin fibers with other protein fibers

M Guthold, W Liu, EA Sparks, LM Jawerth… - Cell biochemistry and …, 2007 - Springer
In the past few years a great deal of progress has been made in studying the mechanical
and structural properties of biological protein fibers. Here, we compare and review the …

Stiffness of pancreatic cancer cells is associated with increased invasive potential

AV Nguyen, KD Nyberg, MB Scott, AM Welsh… - Integrative …, 2016 - academic.oup.com
Metastasis is a fundamentally physical process in which cells are required to deform through
narrow gaps as they invade surrounding tissues and transit to distant sites. In many cancers …

Molecular structure of soluble vimentin tetramers

PJ Vermeire, AV Lilina, HM Hashim, L Dlabolová… - Scientific Reports, 2023 - nature.com
Intermediate filaments (IFs) are essential constituents of the metazoan cytoskeleton. A vast
family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric …