Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chip
L Sun, T Lehnert, MAM Gijs, S Li - Lab on a Chip, 2022 - pubs.rsc.org
Next-generation sequencing (NGS) is an essential technology for DNA identification in
genomic research. DNA fragmentation is a critical step for NGS and doing this on-chip is of …
genomic research. DNA fragmentation is a critical step for NGS and doing this on-chip is of …
DNA fragmentation in complicated flow fields created by micro-funnel shapes
Micro-funnels have been widely applied to produce extensionally dominant flows for DNA
manipulation, such as DNA extension for DNA mapping and DNA fragmentation for gene …
manipulation, such as DNA extension for DNA mapping and DNA fragmentation for gene …
Hydrodynamics-assisted scalable production of boron nitride nanosheets and their application in improving oxygen-atom erosion resistance of polymeric composites
Searching for a method for low-cost, easily manageable, and scalable production of boron
nitride nanosheets (BNNSs) and exploring their novel applications are highly important. For …
nitride nanosheets (BNNSs) and exploring their novel applications are highly important. For …
Modelling DNA extension and fragmentation in contractive microfluidic devices: a Brownian dynamics and computational fluid dynamics approach
S Wu, C Li, Q Zheng, L Xu - Soft Matter, 2018 - pubs.rsc.org
Fragmenting DNA into short pieces is an essential manipulation in many biological studies,
ranging from genome sequencing to molecular diagnosis. Among various DNA …
ranging from genome sequencing to molecular diagnosis. Among various DNA …
A simple approach for effective shearing and reliable concentration measurement of ultra-high-molecular-weight DNA
PA 'Giron'Koetsier, EJ Cantor - BioTechniques, 2021 - Taylor & Francis
Pipetting and concentration measurement of viscous ultra-high-molecular-weight (UHMW)
DNA samples is challenging and often highly imprecise. Effective guidelines for handling …
DNA samples is challenging and often highly imprecise. Effective guidelines for handling …
Microfluidic continuous flow DNA fragmentation based on a vibrating sharp-tip
Fragmentation of DNA into short fragments is of great importance for detecting and studying
DNAs. Current microfluidic methods of DNA fragmentation are either inefficient for …
DNAs. Current microfluidic methods of DNA fragmentation are either inefficient for …
An ultrasonic biosample disruptor with two triangular teeth on its radiation face
Ultrasound has been used in biosample disruption such as disruption of algal cell and DNA.
New structure of ultrasonic biosample disruptor (UBD) needs to be explored to increase the …
New structure of ultrasonic biosample disruptor (UBD) needs to be explored to increase the …
High-Throughput Separation of Long DNA in Deterministic Lateral Displacement Arrays
OE Ström, JP Beech, JO Tegenfeldt - Micromachines, 2022 - mdpi.com
Length-based separation of DNA remains as relevant today as when gel electrophoresis
was introduced almost 100 years ago. While new, long-read genomics technologies have …
was introduced almost 100 years ago. While new, long-read genomics technologies have …
DNA fragmentation in a steady shear flow
We have determined the susceptibility of T4 DNA (166 kilobase pairs, kbp) to fragmentation
under steady shear in a cone-and-plate rheometer. After shearing for at least 30 min at a …
under steady shear in a cone-and-plate rheometer. After shearing for at least 30 min at a …
High efficiency hydrodynamic DNA fragmentation in a bubbling system
DNA fragmentation down to a precise fragment size is important for biomedical applications,
disease determination, gene therapy and shotgun sequencing. In this work, a cheap, easy to …
disease determination, gene therapy and shotgun sequencing. In this work, a cheap, easy to …