The renin-angiotensin system (RAS) is undisputedly one of the most prominent endocrine
(tissue-to-tissue), paracrine (cell-to-cell) and intracrine (intracellular/nuclear) vasoactive …

The renin-angiotensin system has powerful effects in control of the blood pressure and
sodium homeostasis. These actions are coordinated through integrated actions in the …

Background Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …

Abstract Angiotensin-converting enzyme (ACE)—a zinc-dependent dicarboxypeptidase with
two catalytic domains—plays a major part in blood pressure regulation by converting …

Acute respiratory distress syndrome (ARDS), the most severe form of acute lung injury, is a
devastating clinical syndrome with a high mortality rate (30–60%)(refs). Predisposing factors …

A novel human zinc metalloprotease that has considerable homology to human angiotensin-
converting enzyme (ACE)(40% identity and 61% similarity) has been identified. This …

Cardiovascular diseases are predicted to be the most common cause of death worldwide by
2020. Here we show that angiotensin-converting enzyme 2 (ace2) maps to a defined …

Since the first identification of renin by Tigerstedt and Bergmann in 1898, the renin-
angiotensin system (RAS) has been extensively studied. The current view of the system is …

Abstract Background and Objectives Angiotensin-converting enzyme 2 (ACE2) converts
angiotensin II (Ang1-8) to angiotensin 1-7 (Ang1-7), a functional antagonist of Ang1-8, with …

At coitus, human sperm are deposited into the anterior vagina, where, to avoid vaginal acid
and immune responses, they quickly contact cervical mucus and enter the cervix. Cervical …