[HTML][HTML] The chick embryo chorioallantoic membrane (CAM). A multifaceted experimental model

D Ribatti - Mechanisms of development, 2016 - Elsevier
During avian development the mesodermal layers of the allantois and chorion fuse to form
the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich …

The chick embryo chorioallantoic membrane (CAM) assay

D Ribatti - Reproductive toxicology, 2017 - Elsevier
During avian development the mesodermal layers of the allantois and chorion fuse to form
the chorioallantoic membrane (CAM). This structure rapidly expands generating a rich …

Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma

RA Francescone, S Scully, M Faibish, SL Taylor… - Journal of Biological …, 2011 - ASBMB
Glioblastoma is one of the most fatal cancers, characterized by a strong vascularized
phenotype. YKL-40, a secreted glycoprotein, is overexpressed in patients with glioblastomas …

Role of chitinase-like proteins in cancer

J Kzhyshkowska, S Yin, T Liu, V Riabov… - Biological …, 2016 - degruyter.com
Chitinase-like proteins (CLPs) are lectins combining properties of cytokines and growth
factors. Human CLPs include YKL-40, YKL-39 and SI-CLP that are secreted by cancer cells …

Plasma YKL-40: a potential new cancer biomarker?

JS Johansen, NA Schultz, BV Jensen - Future Oncology, 2009 - Taylor & Francis
YKL-40, a 40-kDa secreted glycoprotein, with its gene located on chromosome 1q32. 1, is
produced by cancer cells and inflammatory cells and has a role in inflammation, cell …

High serum YKL-40 concentration is associated with cardiovascular and all-cause mortality in patients with stable coronary artery disease

J Kastrup, JS Johansen, P Winkel… - European heart …, 2009 - academic.oup.com
Aims Macrophages in atherosclerotic plaques secrete YKL-40. We tested the hypothesis if
high serum YKL-40 concentration predicts coronary events and death of patients with stable …

YKL-40 acts as an angiogenic factor to promote tumor angiogenesis

R Shao - Frontiers in Physiology, 2013 - frontiersin.org
A secreted glycoprotein YKL-40 also named chitinase-3-like-1 is normally expressed by
multiple cell types such as macrophages, chondrocytes, and vascular smooth muscle cells …

CHI3L1 plays a role in cancer through enhanced production of pro-inflammatory/pro-tumorigenic and angiogenic factors

S Libreros, R Garcia-Areas… - Immunologic …, 2013 - Springer
Elevated serum levels of a glycoprotein known as chitinase-3-like protein 1 (CHI3L1) have
been correlated with poor prognosis and shorter survival of patients with cancer and …

The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

H Bernard, B Garmy-Susini, N Ainaoui… - Oncogene, 2013 - nature.com
The tumour suppressor p53, involved in DNA repair, cell cycle arrest and apoptosis, also
inhibits blood vessel formation, that is, angiogenesis, a process strongly contributing to …

In ovo model in cancer research and tumor immunology

L Miebach, J Berner, S Bekeschus - Frontiers in Immunology, 2022 - frontiersin.org
Considering cancer not only as malignant cells on their own but as a complex disease in
which tumor cells interact and communicate with their microenvironment has motivated the …