Neurobiology of loneliness, isolation, and loss: integrating human and animal perspectives
EM Vitale, AS Smith - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
In social species such as humans, non-human primates, and even many rodent species,
social interaction and the maintenance of social bonds are necessary for mental and …
social interaction and the maintenance of social bonds are necessary for mental and …
Attachment across the lifespan: examining the intersection of pair bonding neurobiology and healthy aging
Increasing evidence suggests that intact social bonds are protective against age-related
morbidity, while bond disruption and social isolation increase the risk for multiple age …
morbidity, while bond disruption and social isolation increase the risk for multiple age …
[HTML][HTML] Social experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles
Social relationships are dynamic and evolve with shared and personal experiences.
Whether the functional role of social neuromodulators also evolves with experience to shape …
Whether the functional role of social neuromodulators also evolves with experience to shape …
Reciprocal processes of sensory perception and social bonding: an integrated social‐sensory framework of social behavior
Organisms filter the complexity of natural stimuli through their individual sensory and
perceptual systems. Such perceptual filtering is particularly important for social stimuli. A …
perceptual systems. Such perceptual filtering is particularly important for social stimuli. A …
Cholinergic interneurons in the nucleus accumbens are a site of cellular convergence for corticotropin‐releasing factor and estrogen regulation in male and female …
KL Olson, AE Ingebretson… - European Journal of …, 2024 - Wiley Online Library
Cholinergic interneurons (ChIs) act as master regulators of striatal output, finely tuning
neurotransmission to control motivated behaviours. ChIs are a cellular target of many …
neurotransmission to control motivated behaviours. ChIs are a cellular target of many …
Partner separation rescues pair bond-induced decreases in hypothalamic oxytocin neural densities
Studies in prairie voles (Microtus ochrogaster) have shown that although formation of the
pair bond is accompanied by a suite of behavioral changes, a bond between two voles can …
pair bond is accompanied by a suite of behavioral changes, a bond between two voles can …
African striped mice (Rhabdomys pumilio) as a neurobehavioral model for male parental care
Parental care is diversely demonstrated across the animal kingdom, such that active
practitioners and repertoires of parental behavior vary dramatically between and within taxa …
practitioners and repertoires of parental behavior vary dramatically between and within taxa …
Neurobiology and treatment advances for prolonged grief disorder
ZR Donaldson, MK Shear - Neuropsychopharmacology, 2024 - nature.com
Prolonged Grief Disorder (PGD) is a recently identified bereavement outcome added to DSM-
5-TR in 2022. Loss of someone close is a major stressor, and~ 7–10% of bereaved …
5-TR in 2022. Loss of someone close is a major stressor, and~ 7–10% of bereaved …
Varied impacts of social relationships on neuroendocrine state
Social relationships, affiliative social attachments, are important for many species. The best
studied types of relationships are monogamous pair bonds. However, it remains unclear …
studied types of relationships are monogamous pair bonds. However, it remains unclear …
Prairie vole pair bonding and plasticity of the social brain
LC Hiura, ZR Donaldson - Trends in neurosciences, 2023 - cell.com
In monogamous species, pair bonding leads to striking changes in social behavior and
neural circuitry. We outline the cognitive building blocks of monogamous pair bonding in …
neural circuitry. We outline the cognitive building blocks of monogamous pair bonding in …