Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Molecular logic of salt taste reception in special reference to transmembrane channel-like 4 (TMC4)

Y Kasahara, M Narukawa, A Takeuchi… - The Journal of …, 2022 - Springer
The taste is biologically of intrinsic importance. It almost momentarily perceives
environmental stimuli for better survival. In the early 2000s, research into taste reception was …

TMC4 is a novel chloride channel involved in high-concentration salt taste sensation

Y Kasahara, M Narukawa, Y Ishimaru, S Kanda… - The Journal of …, 2021 - Springer
Abstract “Salty taste” sensation is evoked when sodium and chloride ions are present
together in the oral cavity. The presence of an epithelial cation channel that receives Na+ …

The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells

R Fettiplace, DN Furness… - Proceedings of the …, 2022 - National Acad Sciences
Transmembrane channel-like protein 1 (TMC1) is thought to form the ion-conducting pore of
the mechanoelectrical transducer (MET) channel in auditory hair cells. Using single-channel …

[HTML][HTML] VSI: The Anoctamins: Structure and Function:“Intracellular” anoctamins

K Kunzelmann, J Ousingsawat, R Schreiber - Cell Calcium, 2024 - Elsevier
Plasma membrane localized anoctamin 1, 2 and 6 (TMEM16A, B, F) have been examined in
great detail with respect to structure and function, but much less is known about the other …

Wide-ranging cellular functions of ion channels and lipid scramblases in the structurally related TMC, TMEM16 and TMEM63 families

LY Jan, YN Jan - Nature Structural & Molecular Biology, 2024 - nature.com
Abstract Calcium (Ca2+)-activated ion channels and lipid scramblases in the
transmembrane protein 16 (TMEM16) family are structurally related to mechanosensitive ion …

New Tmc1 deafness mutations impact mechanotransduction in auditory hair cells

M Beurg, LA Schimmenti, A Koleilat… - Journal of …, 2021 - Soc Neuroscience
Transmembrane channel-like protein isoform 1 (TMC1) is a major component of the
mechano-electrical transducer (MET) channel in cochlear hair cells and is subject to …

The crustacean antennule: a complex organ adapted for lifelong function in diverse environments and lifestyles

CD Derby - The Biological Bulletin, 2021 - journals.uchicago.edu
The crustacean first antenna, or antennule, has been an experimental model for studying
sensory biology for over 150 years. Investigations have led to a clearer understanding of the …

The transmembrane channel-like 6 (TMC6) in primary sensory neurons involving thermal sensation via modulating M channels

Y An, J Hu, H Hao, W Zhao, X Zhang, J Shao… - Frontiers in …, 2024 - frontiersin.org
Introduction: The transmembrane channel-like (TMC) protein family contains eight members,
TMC1–TMC8. Among these members, only TMC1 and TMC2 have been intensively studied …

Functional role of class III myosins in hair cells

JA Cirilo Jr, LK Gunther, CM Yengo - Frontiers in Cell and …, 2021 - frontiersin.org
Cytoskeletal motors produce force and motion using the energy from ATP hydrolysis and
function in a variety of mechanical roles in cells including muscle contraction, cargo …