During exercise, there is a progressive reduction in the ability to produce muscle forces.
Processes within the nervous system, as well as within the muscles contribute to this fatigue …

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic
disease of unknown aetiology that is recognized by the World Health Organization (WHO) …

At the base of axons sits a unique compartment called the axon initial segment (AIS). The
AIS generates and shapes the action potential before it is propagated along the axon …

This article presents a historical overview and an up-to-date review of hyperthermia-induced
fatigue during exercise in the heat. Exercise in the heat is associated with a …

Brain glycogen stored in astrocytes provides lactate as an energy source to neurons through
monocarboxylate transporters (MCTs) to maintain neuronal functions such as hippocampus …

Serotonergic neuromodulation contributes to enhanced voluntary muscle activation.
However, it is not known how the likely motoneurone receptor candidate (5‐HT2) influences …

It is now accepted that neurons contain and release multiple transmitter substances.
However, we still have only limited insight into the regulation and functional effects of this co …

Acorus tatarinowii Schott (A. tatarinowii) is a natural medicinal plant. It plays an
indispensable role in the treatment of diseases by the empirical medicine system and has …

Neurons implement a variety of plasticity mechanisms to alter their function over timescales
ranging from seconds to days. One powerful means of controlling excitability is to directly …

Key points Animal preparations have revealed that moderate synaptic release of serotonin
(5‐HT) onto motoneurones enhances motor activity via activation of 5‐HT2 receptors …