The objective of lung development is to generate an organ of gas exchange that provides
both a thin gas diffusion barrier and a large gas diffusion surface area, which concomitantly …

Bronchopulmonary dysplasia (BPD) continues to be one of the most common complications
of preterm birth and is characterized histopathologically by impaired lung alveolarization …

It is well established that a number of birth defects are associated with improper formation of
the respiratory tract. Important progress has been made in the identification of components …

Recent advances in epigenetics have made a tremendous impact on our knowledge of
biological phenomena and the environmental stressors on complex diseases …

MicroRNAs are a kind of small and non-coding RNAs, which have been demonstrated to
play an important role in the progression of human cervical cancer. Here, we found that the …

Infants with congenital diaphragmatic hernia (CDH) are at high risk of postnatal mortality due
to lung hypoplasia and arterial pulmonary hypertension. In severe cases, prenatal …

Altered microRNA (miRNA or miR) expression has been reported in chronic obstructive
pulmonary disease (COPD). The present study aimed to identify the involvement of miRNAs …

Objective Bronchopulmonary dysplasia (BPD) is a pulmonary injury related to inflammation
and is a major cause of premature infant death. Long noncoding RNAs (lncRNAs) are …

Background The pathogenesis of congenital diaphragmatic hernia (CDH) and the causes of
pulmonary hypoplasia and hypertension remain unclear. miRNAs have been identified to …

Purpose Tracheal occlusion (TO) reverses pulmonary hypoplasia (PH) in congenital
diaphragmatic hernia (CDH), but its mechanism of action remains poorly understood. Wnt …