The focus of structural biology is shifting from the determination of static structures to the
investigation of dynamical aspects of macromolecular function. With time-resolved …

Protein homo-oligomerization is a very common phenomenon, and approximately half of
proteins form homo-oligomeric assemblies composed of identical subunits. The vast majority …

The combination of high sensitivity and rapid readout makes it possible for electron-counting
detectors to record cryogenic electron microscopy data faster and more accurately without …

Respirasome, as a vital part of the oxidative phosphorylation system, undertakes the task of
transferring electrons from the electron donors to oxygen and produces a proton …

X-ray crystallography is a robust and powerful structural biology technique that provides
high-resolution atomic structures of biomacromolecules. Scientists use this technique to …

Protein Crystallography or Macromolecular Crystallography (MX) started as a new discipline
of science with the pioneering work on the determination of the protein crystal structures by …

X-ray crystallography has long been a key method in solving the three-dimensional structure
of proteins. Structural information is essential for unraveling the molecular function of …

Amidosulfuron (AS) is from the commercial sulfonylurea herbicide family. It is highly effective
against dicot broad-leaf weeds. This herbicide targets acetohydroxyacid synthase (AHAS) …

X-ray free electron lasers deliver photon pulses that are bright enough to observe diffraction
from extremely small crystals at a time scale that outruns their destruction. As crystals are …

Crystallographic fragment screening (CFS) has become one of the major techniques for
screening compounds in the early stages of drug-discovery projects. Following the …