Towards modern-age advanced sensors for the management of neurodegenerative disorders: current status, challenges and prospects

A Gautam - ECS Sensors Plus, 2022 - iopscience.iop.org
Neurodegenerative diseases (NDD) are progressive degenerative disorders of the
neurological system with significant social impact worldwide. Their detection at the initial …

Effects of communicating DNA‐based disease risk estimates on risk‐reducing behaviours

TM Marteau, DP French, SJ Griffin… - Cochrane Database …, 2010 - cochranelibrary.com
Background There are high expectations regarding the potential for the communication of
DNA‐based disease risk estimates to motivate behaviour change. Objectives To assess the …

Big data hurdles in precision medicine and precision public health

M Prosperi, JS Min, J Bian, F Modave - BMC medical informatics and …, 2018 - Springer
Background Nowadays, trendy research in biomedical sciences juxtaposes the term
'precision'to medicine and public health with companion words like big data, data science …

[HTML][HTML] Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of …

JS Goldman, SE Hahn, JW Catania… - Genetics in …, 2011 - Elsevier
Alzheimer disease is the most common cause of dementia. It occurs worldwide and affects
all ethnic groups. The incidence of Alzheimer disease is increasing due, in part, to increased …

Understanding the amyloid hypothesis in Alzheimer's disease

G Paroni, P Bisceglia, D Seripa - Journal of Alzheimer's …, 2019 - content.iospress.com
The amyloid hypothesis (AH) is still the most accepted model to explain the pathogenesis of
inherited Alzheimer's disease (IAD). However, despite the neuropathological overlapping …

Cognitively unimpaired adults' reactions to disclosure of amyloid PET scan results

EA Largent, K Harkins, CH van Dyck, S Hachey… - PloS one, 2020 - journals.plos.org
Importance Clinical guidelines currently recommend against amyloid imaging for cognitively
unimpaired persons. The goal of Alzheimer's disease (AD) prevention, together with …

Considerations regarding a diagnosis of Alzheimer's disease before dementia: a systematic review

J van der Schaar, LNC Visser, FH Bouwman… - Alzheimer's research & …, 2022 - Springer
Abstract Background The NIA-AA research framework proposes a purely biological
definition of Alzheimer's disease (AD). This implies that AD can be diagnosed based on …

Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study

S Chao, JS Roberts, TM Marteau… - Alzheimer Disease & …, 2008 - journals.lww.com
Risk information for Alzheimer disease (AD) may be communicated through susceptibility
gene disclosure, even though this is not currently in clinical use. The REVEAL Study is the …

Ethical and legal considerations of artificial intelligence and algorithmic decision-making in personalized pricing

JA Gerlick, SM Liozu - Journal of Revenue and Pricing Management, 2020 - Springer
The extent to which pricing executives consider consumer perceptions of deception,
fairness, and social justice is positioned within an emerging area of research that …

[HTML][HTML] The ghost in our genes: legal and ethical implications of epigenetics

MA Rothstein, Y Cai, GE Marchant - Health matrix (Cleveland, Ohio …, 2009 - ncbi.nlm.nih.gov
Epigenetics is one of the most scientifically important, and legally and ethically significant,
cutting-edge subjects of scientific discovery. Epigenetics link environmental and genetic …