From chaos to opportunity: decoding cancer heterogeneity for enhanced treatment strategies
A Ottaiano, M Ianniello, M Santorsola, R Ruggiero… - Biology, 2023 - mdpi.com
Simple Summary Cancer is a complex illness marked by aberrant cellular behaviors and
genetic variances, resulting in tumor heterogeneity that presents challenges in cancer …
genetic variances, resulting in tumor heterogeneity that presents challenges in cancer …
Molecular classifications in gastric cancer: A call for interdisciplinary collaboration
C Díaz del Arco, MJ Fernández Aceñero… - International Journal of …, 2024 - mdpi.com
Gastric cancer (GC) is a heterogeneous disease, often diagnosed at advanced stages, with
a 5-year survival rate of approximately 20%. Despite notable technological advancements in …
a 5-year survival rate of approximately 20%. Despite notable technological advancements in …
Liquid biopsy: circulating tumor DNA monitors neoadjuvant chemotherapy response and prognosis in stage II/III gastric cancer
M Zhang, H Yang, T Fu, M Meng, Y Feng… - Molecular …, 2023 - Wiley Online Library
A good response to neoadjuvant chemotherapy (NACT) is strongly associated with a higher
curative resection rate and favorable outcomes for patients with gastric cancer (GC). We …
curative resection rate and favorable outcomes for patients with gastric cancer (GC). We …
Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of …
Y Su, X Zhang, Y Liang, J Sun, C Lu… - Biochimica et Biophysica …, 2024 - Elsevier
Intestinal-type gastric cancer (IGC) is the most frequent type of gastric cancer in high-
incidence populations. The early stages of IGC growth successively include nonatrophic …
incidence populations. The early stages of IGC growth successively include nonatrophic …
Prognostic impact and immunotherapeutic implications of NETosis‐related gene signature in gastric cancer patients
T Xiang, Z Wei, C Ye, G Liu - Journal of Cellular and Molecular …, 2024 - Wiley Online Library
The role of NETosis and its related molecules remains unclear in gastric cancer. The data
used in this study was directly downloaded from the Cancer Genome Atlas (TCGA) …
used in this study was directly downloaded from the Cancer Genome Atlas (TCGA) …
[HTML][HTML] Identification of three immune subtypes characterized by distinct tumor immune microenvironment and therapeutic response in stomach adenocarcinoma
Y Zhu, Y Zhao, Z Cao, Z Chen, W Pan - Gene, 2022 - Elsevier
Background In primary stomach adenocarcinoma (STAD), the tumor immune
microenvironment (TIME) is important for cancer occurrence and progression; however, its …
microenvironment (TIME) is important for cancer occurrence and progression; however, its …
NF-κB in gastric cancer development and therapy
S Chaithongyot, P Jantaree, O Sokolova, M Naumann - Biomedicines, 2021 - mdpi.com
Gastric cancer is considered one of the most common causes of cancer-related death
worldwide and, thus, a major health problem. A variety of environmental factors including …
worldwide and, thus, a major health problem. A variety of environmental factors including …
Epigenome-wide DNA methylation profiling in colorectal cancer and normal adjacent colon using infinium human methylation 450K
R Baharudin, M Ishak, A Muhamad Yusof, S Saidin… - Diagnostics, 2022 - mdpi.com
The aims were to profile the DNA methylation in colorectal cancer (CRC) and to explore
cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the adjacent normal …
cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the adjacent normal …
Metabolic Patterns of High-Invasive and Low-Invasive Oral Squamous Cell Carcinoma Cells Using Quantitative Metabolomics and 13C-Glucose Tracing
W Jiang, T Zhang, H Zhang, T Han, P Ji, Z Ou - Biomolecules, 2023 - mdpi.com
Most current metabolomics studies of oral squamous cell carcinoma (OSCC) are mainly
focused on identifying potential biomarkers for early screening and diagnosis, while few …
focused on identifying potential biomarkers for early screening and diagnosis, while few …
Transcriptomic characterization revealed that METTL7A inhibits melanoma progression via the p53 signaling pathway and immunomodulatory pathway
D Zhang, T Zou, Q Liu, J Chen, M Xiao, A Zheng… - PeerJ, 2023 - peerj.com
ABSTRACT METTL7A is a protein-coding gene expected to be associated with methylation,
and its expression disorder is associated with a range of diseases. However, few research …
and its expression disorder is associated with a range of diseases. However, few research …