The role of structure and biophysical properties in the pleiotropic effects of statins

C Murphy, E Deplazes, CG Cranfield… - International journal of …, 2020 - mdpi.com
Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are
amongst the most prescribed medications worldwide. Most statins work as a competitive …

Exploitation of Sugarcane Bagasse and Environmentally Sustainable Production, Purification, Characterization, and Application of Lovastatin by Aspergillus terreus …

AMAA Ramadan, RM Shehata, HH El-Sheikh, F Ameen… - Molecules, 2023 - mdpi.com
Using the internal transcribed spacer (ITS) region for identification, three strains of
Aspergillus terreus were identified and designated AUMC 15760, AUMC 15762, and AUMC …

[HTML][HTML] Incorporation of simvastatin into lipid membranes: Why deliver a statin in form of inclusion complex with hydrophilic cyclodextrin

A Bartkowiak, D Matyszewska, A Krzak… - Colloids and Surfaces B …, 2021 - Elsevier
In this work, the effects of simvastatin (SIM),(2-hydroxypropyl)-β-cyclodextrin (HPβCD) and
their complex (SIM: HPβCD) on the structure and properties of lipid membranes were …

Modulation of phospholipid bilayer properties by simvastatin

RD Teo, DP Tieleman - The Journal of Physical Chemistry B, 2021 - ACS Publications
Simvastatin (Zocor) is one of the most prescribed drugs for reducing high cholesterol.
Although simvastatin is ingested in its inactive lactone form, it is converted to its active …

Estimating localization of various statins within a POPC bilayer

JO Kuba, Y Yu, JB Klauda - Chemistry and Physics of Lipids, 2021 - Elsevier
As a class of drugs prescribed to heart disease patients, statins are among the most popular
prescription drugs in the world. Over the years, statins have been shown to have beneficial …

The affect of gadolinium ion on micelles and reverse micelles by NMR spectroscopy

AS Tarasov, IZ Rakhmatullin, GS Shurshalova… - Bionanoscience, 2021 - Springer
Paramagnetic gadolinium ions are used as one of the possible contrast agents for magnetic
resonance imaging. Contrast agents interact with living cells. An interesting task is to …

[HTML][HTML] Interaction of the pitavastatin with model membranes

GS Shurshalova, HA Scheidt, M Fischer… - … and Biophysics Reports, 2021 - Elsevier
Pitavastatin is a statin drug that, by competitively inhibiting 3-hydroxy-3-methylglutaryl-
coenzyme A reductase, can lower serum cholesterol levels of low-density lipoprotein (LDL) …

[HTML][HTML] (Gd3+) Complexation with oligopeptide (SFVG) and amyloid peptide (Aβ13–23) in aqueous solution by NMR spectroscopy

AS Tarasov, IZ Rakhmatullin, DS Blokhin… - Results in …, 2023 - Elsevier
Gadolinium (III) ion, which belongs to the subgroup of transition metal ions, has practical
importance for magnetic resonance imaging (MRI) with contrast. The accumulation of …

Grapevine stilbenoids as natural food preservatives: calorimetric and spectroscopic insights into the interaction with model cell membranes

F Saitta, S Mazzini, L Mattio, M Signorelli… - Food & Function, 2021 - pubs.rsc.org
Food contamination with pathogenic microorganisms, such as Listeria monocytogenes,
Salmonella enterica, Staphylococcus aureus and Bacillus cereus, is a common health …