Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Flexibly selecting appropriate actions in response to complex, ever-changing environments
requires both cortical and subcortical regions, which are typically described as participating …

Predictive processing is a computational framework that aims to explain how the brain
processes sensory information by making predictions about the environment and minimizing …

The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …

Neurons in the cortex are heterogeneous, sending diverse axonal projections to multiple
brain regions. Unraveling the logic of these projections requires single-neuron resolution …

The article reviews the history development of artificial neural networks (ANNs), then
compares the differences between ANNs and brain networks in their constituent unit …

The neurons in the cerebral cortex are not randomly interconnected. This specificity in wiring
can result from synapse formation mechanisms that connect neurons, depending on their …

Sensory-guided limb control relies on communication across sensorimotor loops. For active
touch with the hand, the longest loop is the transcortical continuation of ascending …

For half a century now, the barrel cortex of common laboratory rodents has been an
exceptionally useful model for studying the formation of topographically organized maps …

Diversity of cell-types that collectively shape the cortical microcircuit ensures the necessary
computational richness to orchestrate a wide variety of behaviors. The information content …