The suprachiasmatic nuclei as a seasonal clock

CP Coomans, A Ramkisoensing, JH Meijer - Frontiers in …, 2015 - Elsevier
In mammals, the suprachiasmatic nucleus (SCN) contains a central clock that synchronizes
daily (ie, 24-h) rhythms in physiology and behavior. SCN neurons are cell-autonomous …

Synchronization of biological clock neurons by light and peripheral feedback systems promotes circadian rhythms and health

A Ramkisoensing, JH Meijer - Frontiers in neurology, 2015 - frontiersin.org
In mammals, the suprachiasmatic nucleus (SCN) functions as a circadian clock that drives
24-h rhythms in both physiology and behavior. The SCN is a multicellular oscillator in which …

Measuring relative coupling strength in circadian systems

C Schmal, ED Herzog, H Herzel - Journal of biological …, 2018 - journals.sagepub.com
Modern imaging techniques allow the monitoring of circadian rhythms of single cells.
Coupling between these single cellular circadian oscillators can generate coherent periodic …

The seasons within: a theoretical perspective on photoperiodic entrainment and encoding

C Schmal - Journal of Comparative Physiology A, 2024 - Springer
Circadian clocks are internal timing devices that have evolved as an adaption to the
omnipresent natural 24 h rhythmicity of daylight intensity. Properties of the circadian system …

The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus

C Gu, A Ramkisoensing, Z Liu… - Journal of biological …, 2014 - journals.sagepub.com
In mammals, the central clock in the suprachiasmatic nucleus (SCN) controls physiological
and behavioral circadian rhythms and is entrained to the external light-dark cycle. The ability …

Entrainment maps: A new tool for understanding properties of circadian oscillator models

CO Diekman, A Bose - Journal of Biological Rhythms, 2016 - journals.sagepub.com
Circadian oscillators found across a variety of species are subject to periodic external light-
dark forcing. Entrainment to light-dark cycles enables the circadian system to align biological …

Seasonality and light phase-resetting in the mammalian circadian rhythm

KM Hannay, DB Forger, V Booth - Scientific Reports, 2020 - nature.com
We study the impact of light on the mammalian circadian system using the theory of phase
response curves. Using a recently developed ansatz we derive a low-dimensional …

Deconstructing circadian rhythmicity with models and manipulations

SD Pauls, KI Honma, S Honma, R Silver - Trends in Neurosciences, 2016 - cell.com
A master brain clock, localized to the hypothalamic suprachiasmatic nucleus (SCN),
coordinates daily rhythms of physiology and behavior. Within the SCN, interconnected …

[HTML][HTML] Achilles tendinopathy treatment via circadian rhythm regulation

Y Zhang, Y Wu, Y Wang, J Lu, Y Lu, P Wang… - Journal of Advanced …, 2024 - Elsevier
Introduction Achilles tendinopathy (AT) is a prevalent musculoskeletal disorder closely
linked to oxidative stress. Existing evidence suggests a potential link between circadian …

The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods

C Gu, M Tang, H Yang - Scientific Reports, 2016 - nature.com
The main function of the principal clock located in the suprachiasmatic nucleus (SCN) of
mammals is synchronizing the body rhythms to the 24 h light-dark cycle. Additionally, the …