Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin

CY Wong, H Al-Salami, CR Dass - International journal of pharmaceutics, 2018 - Elsevier
Diabetes mellitus is a chronic metabolic health disease affecting the homeostasis of blood
sugar levels. However, subcutaneous injection of insulin can lead to patient non …

Microfluidic assisted synthesis of PLGA drug delivery systems

S Rezvantalab, MK Moraveji - RSC advances, 2019 - pubs.rsc.org
Poly (lactic-co-glycolic acid)(PLGA) is a biocompatible and biodegradable polymer that
recently attracted attention for use as part of drug delivery systems (DDS). In this context …

Machine learning models to accelerate the design of polymeric long-acting injectables

P Bannigan, Z Bao, RJ Hickman, M Aldeghi… - Nature …, 2023 - nature.com
Long-acting injectables are considered one of the most promising therapeutic strategies for
the treatment of chronic diseases as they can afford improved therapeutic efficacy, safety …

Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy?

VT Tran, JP Benoît, MC Venier-Julienne - International journal of …, 2011 - Elsevier
Drug delivery via biodegradable microparticles benefits from both the protection of the
encapsulated drug from hazardous conditions and the controlled release of the …

ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells

C Chittasupho, SX Xie, A Baoum, T Yakovleva… - European journal of …, 2009 - Elsevier
Interaction of leukocyte function associated antigen-1 (LFA-1) on T-lymphoctytes and
intercellular adhesion molecule-1 (ICAM-1) on epithelial cells controls leukocyte adhesion …

[HTML][HTML] Drug delivery systems for prolonged duration local anesthesia

CM Santamaria, A Woodruff, R Yang, DS Kohane - Materials Today, 2017 - Elsevier
Numerous drug delivery systems have been applied to the problem of providing prolonged
duration local anesthesia (PDLA). Here we review the rationale for PDLA, the desirable …

Potent engineered PLGA nanoparticles by virtue of exceptionally high chemotherapeutic loadings

EM Enlow, JC Luft, ME Napier, JM DeSimone - Nano letters, 2011 - ACS Publications
Herein we report the fabrication of engineered poly (lactic acid-co-glycolic acid)
nanoparticles via the PRINT (particle replication in nonwetting templates) process with high …

Building functional materials for health care and pharmacy from microfluidic principles and flow focusing

AM Gañán-Calvo, JM Montanero… - Advanced drug delivery …, 2013 - Elsevier
In this review, we aim at establishing a relationship between the fundamentals of the
microfluidics technologies used in the Pharmacy field, and the achievements accomplished …

Nanobody conjugated PLGA nanoparticles for active targeting of African Trypanosomiasis

JL Arias, JD Unciti-Broceta, J Maceira… - Journal of Controlled …, 2015 - Elsevier
Targeted delivery of therapeutics is an alternative approach for the selective treatment of
infectious diseases. The surface of African trypanosomes, the causative agents of African …

Magnetic solid lipid nanoparticles in hyperthermia against colon cancer

MM de Escalona, E Sáez-Fernández, JC Prados… - International journal of …, 2016 - Elsevier
A reproducible double emulsion/solvent evaporation procedure is developed to formulate
magnetic solid lipid nanoparticles (average size≈ 180 nm) made of iron oxide cores …