The use of induced pluripotent stem cells as a platform for the study of depression

J Villafranco, G Martínez-Ramírez… - Frontiers in …, 2024 - frontiersin.org
The neurobiological mechanisms underlying major depressive disorder (MDD) remain
largely unexplored due to the limited availability of study models in humans. Induced …

Bipolar disorders and schizophrenia: discrete disorders?

M Dines, M Kes, D Ailán, M Cetkovich-Bakmas… - Frontiers in …, 2024 - frontiersin.org
Background With similarities in heritability, neurobiology and symptomatology, the question
has been raised whether schizophrenia and bipolar disorder are truly distinctive disorders or …

The LEADING Guideline: Reporting Standards for Expert Panel, Best-Estimate Diagnosis, and Longitudinal Expert All Data (LEAD) Studies

VC Eijsbroek, K Kjell, HA Schwartz, JR Boehnke… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Background Accurate assessments of symptoms and illnesses are essential for health
research and clinical practice but face many challenges. The absence of a single error-free …

Human pluripotent stem cells as a translational toolkit in psychedelic research in vitro

JA Salerno, S Rehen - Iscience, 2024 - cell.com
Psychedelics, recognized for their impact on perception, are resurging as promising
treatments with rapid onset for mood and substance use disorders. Despite increasing …