Ischemia and reperfusion (I/R) causes a reduction in arterial blood supply to tissues,
followed by the restoration of perfusion and consequent reoxygenation. The reestablishment …

Monocyte-derived macrophages can determine the outcome of the immune response and
whether this response contributes to tissue repair or mediates tissue destruction. In addition …

The main function of chemokines is to guide inflammatory cells in their migration to sites of
inflammation. During the last 2 decades, an expanding number of chemokines and their …

Kidney ischemia–reperfusion injury (IRI) engages both the innate and adaptive immune
responses. Cellular mediators of immunity, such as dendritic cells, neutrophils …

Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …

This study hypothesized that resveratrol, a silencing information regulator 1 (SIRT1)
activator, would counteract the inflammatory signaling associated with radiotherapy-induced …

Abstract The IL-33-type 2 innate lymphoid cell (ILC2) axis has an important role in tissue
homeostasis, inflammation, and wound healing. However, the relative importance of this …

Kidney hypoperfusion during episodes of systemic hypotension or after surgical
procurement for transplantation can lead to tubular cell death via necrosis and apoptosis …

IL-25 is an important immune regulator that can promote Th2 immune response-dependent
immunity, inflammation, and tissue repair in asthma, intestinal infection, and autoimmune …

Autosomal-dominant (AD) polycystic kidney disease (PKD) is a leading cause of renal
failure in the United States, and currently lacks available treatment options to slow disease …