Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Nanomedicines for reactive oxygen species mediated approach: an emerging paradigm for cancer treatment

S Kwon, H Ko, DG You, K Kataoka… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus Growth in the knowledge of cancer biology has led to the emergence and
evolution of cancer nanomedicines by providing the rationale for leveraging nanotechnology …

Photoresponsive biomaterials for targeted drug delivery and 4D cell culture

ER Ruskowitz, CA DeForest - Nature Reviews Materials, 2018 - nature.com
Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Transformable liquid-metal nanomedicine

Y Lu, Q Hu, Y Lin, DB Pacardo, C Wang, W Sun… - Nature …, 2015 - nature.com
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects

S Barua, S Mitragotri - Nano today, 2014 - Elsevier
Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond)

U Lächelt, E Wagner - Chemical reviews, 2015 - ACS Publications
Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Photodynamic therapy of cancer: an update

P Agostinis, K Berg, KA Cengel… - CA: a cancer journal …, 2011 - Wiley Online Library
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

Photodynamic efficiency: from molecular photochemistry to cell death

IOL Bacellar, TM Tsubone, C Pavani… - International journal of …, 2015 - mdpi.com
Photodynamic therapy (PDT) is a clinical modality used to treat cancer and infectious
diseases. The main agent is the photosensitizer (PS), which is excited by light and converted …

Endosomal escape pathways for delivery of biologicals

AK Varkouhi, M Scholte, G Storm, HJ Haisma - Journal of Controlled …, 2011 - Elsevier
Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in …