Gender specific association of RAS gene polymorphism with essential hypertension: a case‐control study

K Dhanachandra Singh, A Jajodia… - BioMed research …, 2014 - Wiley Online Library
Renin‐angiotensin system (RAS) polymorphisms have been studied as candidate risk
factors for hypertension with inconsistent results, possibly due to heterogeneity among …

Computational and pharmacogenomic insights on hypertension treatment: rational drug design and optimization strategies

L Loganathan, K Gopinath… - Current Drug …, 2020 - ingentaconnect.com
Background: Hypertension is a prevalent cardiovascular complication caused by genetic
and nongenetic factors. Blood pressure (BP) management is difficult because most patients …

Association study of M235T and A‐6G polymorphisms in angiotensinogen gene with risk of developing preeclampsia in Iranian population

E Alaee, M Mirahmadi, M Ghasemi… - Annals of Human …, 2019 - Wiley Online Library
Objective Preeclampsia (PE) is a life‐threatening complication of pregnancy that accounts
for 12% of all maternal deaths worldwide. The aim of this study is to investigate the …

Estimation of risk and interaction of single nucleotide polymorphisms at angiotensinogen locus causing susceptibility to essential hypertension: a case control study

B Charita, G Padma, P Sushma… - Journal of the Renin …, 2012 - journals.sagepub.com
Introduction: The risk conferred by the variants and haplotypes of single nucleotide
polymorphisms (SNPs) at human angiotensinogen (AGT) gene to essential hypertension …

Risk conferred by tagged SNPs of AGT gene in causing susceptibility to essential hypertension

G Padma, N Swapna, M Mamata… - Clinical and …, 2014 - Taylor & Francis
Introduction: AGT gene harbors several variants of which 21 are found to be in high linkage
disequilibrium as per Hapmap database. Studies delineating the importance of these tagged …

Structural and dynamic investigation of non‐synonymous variations in Renin–AGT complex revealed altered binding via hydrogen‐bonding network reprogramming …

H Ahmad, A Khan, S Umbreen, T Khan… - Chemical Biology & …, 2022 - Wiley Online Library
Hypertension is one of the major issues worldwide and one of the main factors involved in
heart and kidney failure. Angiotensinogen and renin are key components of the renin …

Angiotensin gene polymorphisms (T174M and M235T) are significantly associated with the hypertensive patients of Tamil Nadu, South India

M Karthikeyan, V Shridevi, R Rose… - … Journal of Human …, 2013 - Taylor & Francis
Hypertension is complex multi factorial disease; the development and progression of
hypertension varies from population to population. The T174M and M235T polymorphisms …

[PDF][PDF] Research Article Gender Specific Association of RAS Gene Polymorphism with Essential Hypertension: A Case-Control Study

KD Singh, A Jajodia, H Kaur, R Kukreti, M Karthikeyan - hypertension - academia.edu
Renin-angiotensin system (RAS) polymorphisms have been studied as candidate risk
factors for hypertension with inconsistent results, possibly due to heterogeneity among …

[引用][C] 高血压辨证分型与血管紧张素原基因M235T 及T174M 多态性关系

王伟, 李芳琼, 李亚平 - 浙江中医杂志, 2011