TERRA is a class of telomeric repeat-containing RNAs that are expressed from telomeres in
multiple organisms. TERRA transcripts play key roles in telomere maintenance and their …

The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …

Telomeres are involved in the maintenance of chromosomes and the prevention of genome
instability. Despite this central importance, significant variation in telomere length has been …

Using long-read sequencing, we assembled and unzipped the polyploid genomes of
Meloidogyne incognita, M. javanica and M. arenaria, three of the most devastating plant …

Several aspects of telomere biology are regulated by the telomeric repeat-containing RNA
TERRA. While TERRA expression is conserved through evolution, species-specific …

After decades of research, our knowledge of the complexity of cancer mechanisms,
elegantly summarized as 'hallmarks of cancer', is expanding, as are the therapeutic …

Telomeres are nucleoprotein complexes at the ends of chromosomes and are indispensable
for the protection and lengthening of terminal DNA. Despite the evolutionarily conserved …

Telomeres are bound by dedicated proteins, which protect them from DNA damage and
regulate telomere length homeostasis. In the nematode Caenorhabditis elegans, a …

Eukaryotic chromosomes typically end in 3′ telomeric overhangs. The safeguarding of
telomeric single-stranded DNA overhangs is carried out by factors related to the protection of …

Telomeres are specialized protein–DNA structures that protect chromosome ends. In
budding yeast, telomeres form clusters at the nuclear periphery. By imaging telomeres in …