Background review for the '2020 European guideline for the diagnosis and treatment of gonorrhoea in adults'

M Unemo, JDC Ross, AB Serwin… - … journal of STD & …, 2021 - journals.sagepub.com
Gonorrhoea is a major public health concern globally. Increasing incidence and sporadic
ceftriaxone-resistant cases, including treatment failures, are growing concerns. The 2020 …

World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international …

M Unemo, MM Lahra, M Cole, P Galarza… - Sexual …, 2019 - CSIRO Publishing
Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious public health problem,
compromising the management and control of gonorrhoea globally. Resistance in N …

WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational study

M Unemo, MM Lahra, M Escher, S Eremin… - The Lancet …, 2021 - thelancet.com
Background Gonorrhoea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are
major health concerns globally. Increased global surveillance of gonococcal AMR is …

Gonorrhoea

M Unemo, HS Seifert, EW Hook III, S Hawkes… - Nature Reviews …, 2019 - nature.com
The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI)
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …

Diagnosing sexually transmitted infections in resource‐constrained settings: challenges and ways forward

TEC Wi, FJ Ndowa, C Ferreyra… - Journal of the …, 2019 - Wiley Online Library
Introduction Sexually transmitted infections (STI s) remain prevalent and are increasing in
several populations. Appropriate STI diagnosis is crucial to prevent the transmission and …

Antimicrobial Resistance in Neisseria gonorrhoeae and Treatment of Gonorrhea

M Unemo, D Golparian, DW Eyre - Neisseria gonorrhoeae: methods and …, 2019 - Springer
Gonorrhea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are major public
health concerns globally. Dual antimicrobial therapy (mainly ceftriaxone 250–500 mg× 1 …

The Laboratory Diagnosis of Neisseria gonorrhoeae: Current Testing and Future Demands

T Meyer, S Buder - Pathogens, 2020 - mdpi.com
The ideal laboratory test to detect Neisseria gonorrhoeae (Ng) should be sensitive, specific,
easy to use, rapid, and affordable and should provide information about susceptibility to …

High susceptibility to zoliflodacin and conserved target (GyrB) for zoliflodacin among 1209 consecutive clinical Neisseria gonorrhoeae isolates from 25 European …

M Unemo, J Ahlstrand, L Sánchez-Busó… - Journal of …, 2021 - academic.oup.com
Objectives Novel antimicrobials for treatment of gonorrhoea are imperative. The first-in-class
spiropyrimidinetrione zoliflodacin is promising and currently in an international Phase 3 …

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

K Hsieh, JH Melendez, CA Gaydos, TH Wang - Lab on a Chip, 2022 - pubs.rsc.org
The incidence rates of sexually transmitted infections (STIs), including the four major curable
STIs–chlamydia, gonorrhea, trichomoniasis and, syphilis–continue to increase globally …

Antimicrobial resistance prediction in Neisseria gonorrhoeae: current status and future prospects

D Golparian, M Unemo - Expert Review of Molecular Diagnostics, 2022 - Taylor & Francis
Introduction Several nucleic acid amplification tests (NAATs), mostly PCRs, to detect
antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae are …