Origins of HIV and the AIDS pandemic

PM Sharp, BH Hahn - Cold Spring …, 2011 - perspectivesinmedicine.cshlp.org
Acquired immunodeficiency syndrome (AIDS) of humans is caused by two lentiviruses,
human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2). Here, we describe the …

[HTML][HTML] Wild great apes as sentinels and sources of infectious disease

S Calvignac-Spencer, SAJ Leendertz… - Clinical Microbiology …, 2012 - Elsevier
Emerging zoonotic infectious diseases pose a serious threat to global health. This is
especially true in relation to the great apes, whose close phylogenetic relationship with …

Origin of the HIV-1 group O epidemic in western lowland gorillas

M D'arc, A Ayouba, A Esteban… - Proceedings of the …, 2015 - National Acad Sciences
HIV-1, the cause of AIDS, is composed of four phylogenetic lineages, groups M, N, O, and P,
each of which resulted from an independent cross-species transmission event of simian …

The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression

Q Wang, KM Clark, R Tiwari, N Raju, GK Tharp… - Cell, 2024 - cell.com
While CD4+ T cell depletion is key to disease progression in people living with HIV and SIV-
infected macaques, the mechanisms underlying this depletion remain incompletely …

Citrus tristeza virus: Evolution of Complex and Varied Genotypic Groups

SJ Harper - Frontiers in Microbiology, 2013 - frontiersin.org
Amongst the Closteroviridae, Citrus tristeza virus (CTV) is almost unique in possessing a
number of distinct and characterized strains, isolates of which produce a wide range of …

Cross-species transmission of simian retroviruses: how and why they could lead to the emergence of new diseases in the human population

S Locatelli, M Peeters - Aids, 2012 - journals.lww.com
The HIV-1 group M epidemic illustrates the extraordinary impact and consequences
resulting from a single zoonotic transmission. Exposure to blood or other secretions of …

Non-M variants of human immunodeficiency virus type 1

T Mourez, F Simon, JC Plantier - Clinical microbiology reviews, 2013 - Am Soc Microbiol
The AIDS pandemic that started in the early 1980s is due to human immunodeficiency virus
type 1 (HIV-1) group M (HIV-M), but apart from this major group, many divergent variants …

Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir

Y Li, JB Ndjango, GH Learn, MA Ramirez… - Journal of …, 2012 - Am Soc Microbiol
Chimpanzees in west central Africa (Pan troglodytes troglodytes) are endemically infected
with simian immunodeficiency viruses (SIVcpz Ptt) that have crossed the species barrier to …

SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations

D Ma, A Jasinska, J Kristoff, JP Grobler, T Turner… - PLoS …, 2013 - journals.plos.org
Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due
to difficulty in collecting and storing samples on site and the lack of analytical reagents …

Non-human primates in HIV research: Achievements, limits and alternatives

T Garcia-Tellez, N Huot, MJ Ploquin, P Rascle… - Infection, Genetics and …, 2016 - Elsevier
An ideal model for HIV-1 research is still unavailable. However, infection of non-human
primates (NHP), such as macaques, with Simian Immunodeficiency Virus (SIV) recapitulates …