There is emerging awareness that subchondral bone remodeling plays an important role in
the development of osteoarthritis (OA). This review presents recent investigations on the …

In the knee joint, the purpose of the cartilage-bone interface is to maintain structural integrity
of the osteochondral unit during walking, kneeling, pivoting, and jumping–during which …

This work investigated the ability of co-cultures of articular chondrocytes and mesenchymal
stem cells (MSCs) to repair articular cartilage in osteochondral defects. Bovine articular …

Background: Subchondral drilling is an established marrow stimulation technique.
Hypothesis: Osteochondral repair is improved when the subchondral bone is perforated with …

Background: Microfracture (MFx) is one of the most common techniques used for the
treatment of articular cartilage defects, although recently there has been a trend toward the …

Background: Marrow stimulation techniques such as subchondral drilling are clinically
important treatment options for symptomatic small cartilage defects. Little is known about …

Alterations of the subchondral bone are pathological features associated with spontaneous
osteochondral repair and with articular cartilage repair procedures. The aim of this review is …

Increasing evidences show that subchondral bone may play a significant role in the repair or
progression of cartilage damage in situ. However, the exact change of subchondral bone …

Marrow stimulation has been performed for more than 45 years beginning with the simple
drilling of bony surfaces, burring or “abrading” the sclerotic lesion, and more recently using …

This is a review on talus osteochondritis dissecans and talus osteochondral lesions. A
majority of the osteochondral lesions are associated with trauma while the cause of pure …