Breast cancer represents one of the most frequently encountered cancer types among
women worldwide. Thioredoxin reductase 1 (TrxR1) is a therapeutic target for breast cancer …

In the present study, we demonstrate the coaction of thioredoxin and glutathione (GSH)
systems in mouse liver against iron overload‐induced oxidative stress (OS). Mice were …

Lung cancer is the leading cause of cancer‐related deaths all over the world. Therefore, it
has gained importance in the development of new chemotherapeutic strategies to identify …

A thiol compound, glutathione, is essential for healthy cell defence against xenobiotics and
oxidative stress. Glutathione reductase (GR) and glutathione S‐transferase (GST) are two …

In this study, we sought to determine how well naringenin, hesperidin, and quercetin
prevented damage brought on by radiotherapy. During the investigation, 48 adult female …

This study was conducted to compare the efficacy of the mouse hepatic and renal
antioxidant systems against inflammation-induced oxidative stress. Increased Il-1 and Il-6 …

Photodynamic therapy (PDT) is currently regarded as a promising method for the treatment
of oncological diseases. However, it involves a number of limitations related to the specific …

Objective Triple negative breast cancer (TNBC) is the most invasive breast cancer subtype
enriched with cancer stem cells. TNBCs do not express estrogen, progesterone, or human …

GSTs catalyze detoxification reactions of harmful xenobiotics via conjugation with
glutathione (GSH) while glutathione reductase (GR) is the sole enzyme that acts in the …

Perfluorooctanoic acid (PFOA) is tumorigenic in rats and mice and potentially tumorigenic in
humans. Here, we studied long-term PFOA exposure with an in vitro transformation model …