In vitro cardiac modeling has taken great strides in the past decade. While most cell and
engineered tissue models have focused on cell and tissue contractile function as readouts …

Highlights•Organ-on-a-chip technology has the potential to improve the success of drug
discovery.•Environmental cues and inter-organ communication increase physiological …

Variations in mechanical properties of the extracellular matrix occurs in various processes,
such as tissue fibrosis. The impact of changes in tissue stiffness on cell behaviour are …

There is evidence demonstrating that heart failure (HF) occurs in 1–2% of the global
population and is often accompanied by comorbidities which contribute to increasing the …

Cell-derived extracellular matrix (ECM) has become increasingly popular in tissue
engineering applications due to its ability to provide tailored signals for desirable cellular …

Myocardial infarctions are one of the most common forms of cardiac injury and death
worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium …

Cardiac tissue engineering (CTE) is a rising field of research aiming to provide strategies to
repair or regenerate damaged heart tissue after events like myocardial infarction. Here, poly …

In this work, we report the design and fabrication of a light-addressable, paper-based
nanocomposite scaffold for optical pacing and read-out of in vitro grown cardiac tissue. The …

Cardiac tissue engineering aims at creating contractile structures that can optimally
reproduce the features of human cardiac tissue. These constructs are becoming valuable …

The extracellular matrix (ECM) actively participates in diverse aspects of cardiovascular
development and physiology as well as during disease development and progression. ECM …