The effect of apolipoprotein E genotype on spatial processing in humans: a meta-analysis and systematic review

J Daly, F De Luca, SC Berens, AP Field, JM Rusted… - Cortex, 2024 - Elsevier
The ε4 allele of the apolipoprotein E (APOE4) gene is an established risk factor for
Alzheimer's disease but its impact on cognition in healthy adults across the lifespan is …

Scan once, analyse many: using large open-access neuroimaging datasets to understand the brain

CR Madan - Neuroinformatics, 2022 - Springer
We are now in a time of readily available brain imaging data. Not only are researchers now
sharing data more than ever before, but additionally large-scale data collecting initiatives …

[HTML][HTML] Air pollution exposure during pregnancy and childhood, APOE ε4 status and Alzheimer polygenic risk score, and brain structural morphology in …

E Essers, AC Binter, A Neumann, T White… - Environmental …, 2023 - Elsevier
Background Air pollution exposure is associated with impaired neurodevelopment, altered
structural brain morphology in children, and neurodegenerative disorders. Differential …

Vascular dysfunction is central to alzheimer's disease pathogenesis in APOE e4 carriers

AN McCorkindale, HD Mundell, B Guennewig… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia and the leading risk factor,
after age, is possession of the apolipoprotein E epsilon 4 allele (APOE4). Approximately …

Memory precision of object-location binding is unimpaired in APOE ε4-carriers with spatial navigation deficits

HM Gellersen, G Coughlan, M Hornberger… - Brain …, 2021 - academic.oup.com
Research suggests that tests of memory fidelity, feature binding and spatial navigation are
promising for early detection of subtle behavioural changes related to Alzheimer's disease …

Genetic association of apolipoprotein E genotype with EEG alpha rhythm slowing and functional brain network alterations during normal aging

NV Ponomareva, TV Andreeva, M Protasova… - Frontiers in …, 2022 - frontiersin.org
The ε4 allele of the apolipoprotein E (APOE 4+) genotype is a major genetic risk factor for
Alzheimer's disease (AD), but the mechanisms underlying its influence remain incompletely …

[HTML][HTML] Redox-associated changes in healthy individuals at risk of Alzheimer's disease. A ten-year follow-up study

M Nepomuceno, P Monllor, MJ Cardells, A Ftara… - Free Radical Biology …, 2024 - Elsevier
Carrying an allele 4 of the apolipoprotein E (ApoE) is the best-established genetic risk factor
to develop Alzheimer's disease (AD). Fifty percent of ApoE4/4 individuals develop the …

[HTML][HTML] Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a …

JN Browndyke, MC Wright, R Yang, A Syed… - British Journal of …, 2021 - Elsevier
Background Cognitive dysfunction after surgery is a major issue in older adults. Here, we
determined the effect of APOE4 on perioperative neurocognitive function in older patients …

A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank

V Heise, A Offer, W Whiteley, CE Mackay… - Translational …, 2024 - nature.com
Alzheimer's disease (AD) risk is increased in carriers of the apolipoprotein E (APOE) ε4
allele and decreased in ε2 allele carriers compared with the ε3ε3 genotype. The aim of this …

Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria

R Milton, F Modibbo, D Gillespie, FI Alkali… - BMC pregnancy and …, 2022 - Springer
Background Almost two million stillbirths occur annually, most occurring in low-and middle-
income countries. Nigeria is reported to have one of the highest stillbirth rates on the African …