Overcoming the blood–brain barrier. challenges and tricks for CNS drug delivery

LA Bors, F Erdő - Scientia Pharmaceutica, 2019 - mdpi.com
Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

Applications and strategies in nanodiagnosis and nanotherapy in lung cancer

C Woodman, G Vundu, A George, CM Wilson - Seminars in cancer biology, 2021 - Elsevier
Lung cancer is the second most common cancer and the leading cause of death in both men
and women in the world. Lung cancer is heterogeneous in nature and diagnosis is often at …

Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in …

P Ganesan, P Ramalingam… - International journal …, 2018 - Taylor & Francis
Solid lipid nanoparticle (SLN) delivery systems have a wide applicability in the delivery of
phyto-bioactive compounds to treat various chronic diseases, including diabetes, cancer …

BDNF and pro-BDNF in serum and exosomes in major depression: Evolution after antidepressant treatment

T Gelle, RA Samey, B Plansont, B Bessette… - Progress in Neuro …, 2021 - Elsevier
Background The study of clinically related biological indicators in Major Depression (MD) is
important. The Brain Derived Neurotrophic Factor (BDNF) appears to play an important role …

Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery

P Kesharwani, A Gothwal, AK Iyer, K Jain… - Drug discovery today, 2018 - Elsevier
Highlights•Dendrimer-based hybrid systems are an emerging platform in the field of drug
delivery.•Hybrid nanomaterials are an important strategy in the field of nanomedicine.• …

The delivery challenge in neurodegenerative disorders: the nanoparticles role in Alzheimer's disease therapeutics and diagnostics

C De la Torre, V Ceña - Pharmaceutics, 2018 - mdpi.com
Alzheimer's disease (AD) is one of the main causes of disability and dependency among
elderly people. AD is a neurodegenerative disorder characterized by a progressive and …

Nanoconstructs as a versatile tool for detection and diagnosis of Alzheimer biomarkers

D Gopalan, A Pandey, AT Alex, G Kalthur… - …, 2021 - iopscience.iop.org
The current review focuses towards the advancements made in the past decade in the field
of nanotechnology for the early Alzheimer's disease (AD) diagnosis. This review includes …

Preventing obstructions of nanosized drug delivery systems by the extracellular matrix

L Tomasetti, M Breunig - Advanced Healthcare Materials, 2018 - Wiley Online Library
Although nanosized drug delivery systems are promising tools for the treatment of severe
diseases, the extracellular matrix (ECM) constitutes a major obstacle that endangers …

[HTML][HTML] Comparison of oncolytic virotherapy and nanotherapy as two new miRNA delivery approaches in lung cancer

AG Alvanegh, SM Ganji, M Tavallaie, A Rafati… - Biomedicine & …, 2021 - Elsevier
Lung cancer is known as the second leading cause of cancer death. Finding ways to detect
early-stage lung cancer can remarkably increase the survival rate. Biomarkers such as …

Silver sulfadiazine encapsulated in lipid-based nanocarriers for burn treatment

H Razavi, MH Darvishi, S Janfaza - Journal of Burn Care & …, 2018 - academic.oup.com
Burn injuries are at risk of bacterial infection because of the damaged skin and reduced
immune responses. Silver sulfadiazine, a potent antibacterial agent, is considered as a …