Neutrophil extracellular traps and long COVID

A Shafqat, MH Omer, I Albalkhi… - Frontiers in …, 2023 - frontiersin.org
Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …

How neutrophils shape the immune response: reassessing their multifaceted role in health and disease

A Shafqat, JA Khan, AY Alkachem, H Sabur… - International Journal of …, 2023 - mdpi.com
Neutrophils are the most abundant of the circulating immune cells and are the first to be
recruited to sites of inflammation. Neutrophils are a heterogeneous group of immune cells …

Oxidative stress as a culprit in diabetic kidney disease

S Su, Z Ma, H Wu, Z Xu, H Yi - Life Sciences, 2023 - Elsevier
Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Neutrophils extracellular traps and ferroptosis in diabetic wounds

Y Huang, Y Ding, B Wang, Q Ji… - International wound …, 2023 - Wiley Online Library
Wound healing is an extremely complex process involving multiple levels of cells and
tissues. It is mainly completed through four stages: haemostasis, inflammation, proliferation …

Diabetic complications and prospective immunotherapy

L Reynolds, Z Luo, K Singh - Frontiers in Immunology, 2023 - frontiersin.org
The incidence of Diabetes Mellitus is increasing globally. Individuals who have been
burdened with diabetes for many years often develop complications as a result of …

Spontaneous NETosis in diabetes: a role of hyperglycemia mediated ROS and autophagy

A Farhan, G Hassan, SHL Ali, Z Yousaf… - Frontiers in …, 2023 - frontiersin.org
Type 2-diabetes, particularly poorly controlled diabetes, is a risk factor for several infections
such as lower respiratory tract and skin infections. Hyperglycemia, a characteristic …

Metformin reverses impaired osteogenesis due to hyperglycemia-induced neutrophil extracellular traps formation

W Zhu, D Xu, J Mei, B Lu, Q Wang, C Zhu, X Zhang… - Bone, 2023 - Elsevier
Diabetic patients suffer from delayed fracture healing and impaired osteogenic function, but
the underlying pathophysiological mechanisms are not fully understood. Neutrophil …

Spontaneous neutrophil extracellular traps release are inflammatory markers associated with hyperglycemia and renal failure on diabetic retinopathy

FS Magaña-Guerrero, JE Aguayo-Flores… - Biomedicines, 2023 - mdpi.com
Diabetic retinopathy (DR) is the major microvascular complication of diabetes and causes
vitreous traction and intraretinal hemorrhages leading to retinal detachment and total …

Oxidative Stress: A Culprit in the Progression of Diabetic Kidney Disease

N Wang, C Zhang - Antioxidants, 2024 - mdpi.com
Diabetic kidney disease (DKD) is the principal culprit behind chronic kidney disease (CKD),
ultimately developing end-stage renal disease (ESRD) and necessitating costly dialysis or …

A New Application for Cenicriviroc, a Dual CCR2/CCR5 Antagonist, in the Treatment of Painful Diabetic Neuropathy in a Mouse Model

A Bober, A Piotrowska, K Pawlik… - International …, 2024 - pmc.ncbi.nlm.nih.gov
The ligands of chemokine receptors 2 and 5 (CCR2 and CCR5, respectively) are associated
with the pathomechanism of neuropathic pain development, but their role in painful diabetic …