Accelerating enzyme discovery and engineering with high-throughput screening
Covering: up to August 2024 Enzymes play an essential role in synthesizing value-added
chemicals with high specificity and selectivity. Since enzymes utilize substrates derived from …
chemicals with high specificity and selectivity. Since enzymes utilize substrates derived from …
[HTML][HTML] Searching for the optimal microbial factory: high-throughput biosensors and analytical techniques for screening small molecules
E O'Connor, J Micklefield, Y Cai - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•Engineering for the bioproduction of natural products is bottlenecked by
screening.•To overcome this, we explore advancements in biosensors and analytical …
screening.•To overcome this, we explore advancements in biosensors and analytical …
Pillar Array Mixer for Postcolumn Derivatization Integrated into Liquid Chromatography-Based Microfluidic Device
M Isokawa, K Nakanishi, T Kanamori… - Analytical …, 2024 - ACS Publications
The chemical derivatization of target analytes can enhance the sensitivity and selectivity of
separation-based methods for metabolite analysis using microfluidic devices. However, the …
separation-based methods for metabolite analysis using microfluidic devices. However, the …
Optimizing Escherichia coli strains and fermentation processes for enhanced L-lysine production: a review
Z Wu, T Chen, W Sun, Y Chen, H Ying - Frontiers in Microbiology, 2024 - frontiersin.org
lysine is an essential amino acid with significant importance, widely used in the food, feed,
and pharmaceutical industries. To meet the increasing demand, microbial fermentation has …
and pharmaceutical industries. To meet the increasing demand, microbial fermentation has …
Coupling of droplet-on-demand microfluidcs with ESI/MS to study single-cell catalysis
Droplet microfluidics provides an efficient method for analysing reactions within the range of
nanoliters to picoliters. However, the sensitive, label-free and versatile detection with ESI/MS …
nanoliters to picoliters. However, the sensitive, label-free and versatile detection with ESI/MS …