[HTML][HTML] Sex differences in frailty among older adults

RS Zeidan, T McElroy, L Rathor, MS Martenson… - Experimental …, 2023 - Elsevier
By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …

Women's experiences of health-related communicative disenfranchisement

CM Thompson, S Babu, S Makos - Health Communication, 2023 - Taylor & Francis
Women's inequitable healthcare experiences are epistemic injustices by which women are
discredited and harmed in their position as knowers of their health and their bodies. Drawing …

[HTML][HTML] Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort

B Grünhagel, M Borggrewe, SH Hagen, SM Ziegler… - Iscience, 2023 - cell.com
Summary Type I interferons (IFN-I) are important mediators of antiviral immunity and
autoimmune diseases. Female plasmacytoid dendritic cells (pDCs) exert an elevated …

Contributions of Synthetic Chemicals to Autoimmune Disease Development and Occurrence

NN Kosarek, EV Preston - Current Environmental Health Reports, 2024 - Springer
Recent studies have provided additional evidence for the associations of exposure to
synthetic chemicals with certain autoimmune conditions. However, impacts on other …

Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender

A Maddalon, L Cari, M Iulini, MN Alhosseini… - Archives of …, 2023 - Springer
Humans can be exposed to endocrine disruptors (EDs) in numerous ways. EDs can interfere
with endogenous hormones at different levels, resulting in numerous adverse human health …

Retrospective analysis of clinical trial safety data for pembrolizumab reveals the effect of co-occurring infections on immune-related adverse events

T Makunts, K Burkhart, R Abagyan, P Lee - PloS one, 2022 - journals.plos.org
Biologics targeting PD-1, PD-L1, and CTLA-4 immune checkpoint proteins have been used
in a variety of tumor types including small and non-small cell lung cancers, melanoma, and …

Sex-and species-associated differences in complement-mediated immunity in humans and rhesus macaques

NS Kelkar, BS Goldberg, J Dufloo, T Bruel, O Schwartz… - Mbio, 2024 - Am Soc Microbiol
The complement system can be viewed as a “moderator” of innate immunity,“instructor” of
humoral immunity, and “regulator” of adaptive immunity. While sex is known to affect …

The immunomodulatory effect of oral NaHCO3 is mediated by the splenic nerve: multivariate impact revealed by artificial neural networks

MR Alvarez, H Alkaissi, AM Rieger, GR Esber… - Journal of …, 2024 - Springer
Stimulation of the inflammatory reflex (IR) is a promising strategy for treating systemic
inflammatory disorders. Recent studies suggest oral sodium bicarbonate (NaHCO3) as a …

A nationwide study of patients hospitalized with indeterminate colitis: a comparison with Crohn's disease and ulcerative colitis

S Prakash, T Tanaka, D Ashat - International journal of colorectal disease, 2023 - Springer
Purpose Indeterminate colitis (IC) is subtype of colonic inflammatory bowel disease (IBD)
that has features of both Crohn's disease (CD) and ulcerative colitis (UC). There have also …

Autoimmunity and Diseases

AJ Alkhatib - The Role of Microbes in Autoimmune Diseases: New …, 2022 - Springer
This chapter introduces several diseases that can be mediated by autoimmunity including
diabetes, cancers, and others. Immunopathological details were explored. The author …