MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology

HS Chawra, M Agarwal, A Mishra, SS Chandel… - … -Research and Practice, 2024 - Elsevier
Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

[HTML][HTML] Non-coding RNA as a biomarker in lung cancer

C Suri, S Swarnkar, L Bhaskar, HK Verma - Non-coding RNA, 2024 - mdpi.com
Introduction: Lung cancer remains one of the most prevalent and deadly cancers globally,
with high mortality rates largely due to late-stage diagnosis, aggressive progression, and …

Circular RNAs in the KRAS pathway: Emerging players in cancer progression

MS Hussain, E Moglad, M Afzal, P Bansal… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

MS Hussain, E Moglad, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …

Supervised contrastive knowledge graph learning for ncRNA-disease association prediction

Y Wang, X Xie, Y Wang, N Sheng, L Huang… - Expert Systems with …, 2025 - Elsevier
Accurately identifying potential disease-related non-coding RNAs (ncRNAs), including
circular RNAs (circRNAs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), is …

Overcoming chemoresistance and radio resistance in prostate cancer: The emergent role of non-coding RNAs

M Sarfraz, L Eltaib, SMB Asdaq, A Guetat… - … -Research and Practice, 2024 - Elsevier
Prostate cancer (PCa) continues to be a major health concern worldwide, with its resistance
to chemotherapy and radiation therapy presenting major hurdles in successful treatment …

Unravelling the role of long non-coding RNAs in modulating the Hedgehog pathway in cancer

SS Chandel, A Mishra, G Dubey, RP Singh… - … -Research and Practice, 2024 - Elsevier
Cancer is a multifactorial pathological condition characterized by uncontrolled cellular
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …

Non-coding RNAs (ncRNAs) as Therapeutic Targets and Biomarkers in Oligodendroglioma

M Imran, ASA Altamimi, MA Babu, K Goyal… - … -Research and Practice, 2024 - Elsevier
Oligodendrogliomas (ODGs) are neuroepithelial tumors that need personalized treatment
plans because of their unique molecular and histological features. Non-coding RNAs form …

[HTML][HTML] lncRNA WAC-AS1 promotes the progression of gastric cancer through miR-204-5p/HOXC8 axis

Y Liu, K Li, Y Gao, Y Feng, X Zhao, R Hou - Translational Oncology, 2024 - Elsevier
LncRNAs affect tumorigenesis, and although the genesis, regulation and physiological
mechanism of lncRNAs in gastric cancer (GC) have been reported, the research of lncRNAs …