Switchable and dynamic G-quadruplexes and their applications

J Dong, MP O'Hagan, I Willner - Chemical Society Reviews, 2022 - pubs.rsc.org
G-Quadruplexes attract growing interest as functional constituents in biology, chemistry,
nanotechnology, and material science. In particular, the reversible dynamic reconfiguration …

Functional DNA sensors integrated with nucleic acid signal amplification strategies for non-nucleic acid targets detection

Y Zhu, J Wu, Q Zhou - Biosensors and Bioelectronics, 2023 - Elsevier
In addition to carrying and transmitting genetic material, some DNA molecules have specific
binding ability or catalytic function. DNA with this special function is collectively referred to as …

On‐site non‐enzymatic orthogonal activation of a catalytic DNA circuit for self‐reinforced in vivo MicroRNA imaging

S He, S Yu, R Li, Y Chen, Q Wang, Y He… - Angewandte …, 2022 - Wiley Online Library
The wide extracellular‐intracellular distribution of microRNA requires the on‐site, robust and
efficient activation of catalytic DNA circuits inside live cells. Herein, we develop an efficient …

A Smart Deoxyribozyme‐Programmable Catalytic DNA Circuit for High‐Contrast MicroRNA Imaging

Y He, Q Wang, C Hong, R Li, J Shang, S Yu… - Angewandte …, 2023 - Wiley Online Library
Synthetic catalytic DNA circuits have been recognized as a promising signal amplification
toolbox for sensitive intracellular imaging, yet their selectivity and efficiency are always …

Entropy-driven amplified electrochemiluminescence biosensor for RdRp gene of SARS-CoV-2 detection with self-assembled DNA tetrahedron scaffolds

Z Fan, B Yao, Y Ding, J Zhao, M Xie, K Zhang - Biosensors and …, 2021 - Elsevier
Dependable, specific and rapid diagnostic methods for severe acute respiratory syndrome β-
coronavirus (SARS-CoV-2) detection are needed to promote public health interventions for …

DNA logic circuits for cancer theranostics

J Chen, S Fu, C Zhang, H Liu, X Su - Small, 2022 - Wiley Online Library
Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment
(TME) and biomarkers has been an emerging approach for precision medicine. DNA …

A Telomerase‐Assisted Strategy for Regeneration of DNA Nanomachines in Living Cells

Q Zhang, Y Wang, W Wang, Q Min… - Angewandte …, 2023 - Wiley Online Library
DNA nanomachines have been engineered into diverse personalized devices for diagnostic
imaging of biomarkers; however, the regeneration of DNA nanomachines in living cells …

Dynamic reconfigurable DNA nanostructures, networks and materials

J Wang, Z Li, I Willner - Angewandte Chemie, 2023 - Wiley Online Library
DNA nanotechnology relies on the structural and functional information encoded in nucleic
acids. Specifically, the sequence‐guided reconfiguration of nucleic acids by auxiliary …

Exploration of Water-Soluble Natural AIEgens boosting label-free turn-on fluorescent sensing in a DNA hydrogel

X Wang, Z Wang, F Dong, D Yang, L Yin… - Analytical …, 2023 - ACS Publications
Various aggregation-induced emission luminogens (AIEgens) have been developed and
applied in different areas in recent years. However, AIEgens generally can aggregate and …

Recent advances in DNA walker machines and their applications coupled with signal amplification strategies: A critical review

M Xu, D Tang - Analytica Chimica Acta, 2021 - Elsevier
DNA walkers, a type of dynamic nanomachines, have become the subject of burgeoning
research in the field of biology. These walkers are powered by driving forces based on …