Mechanism-based myofilament manipulation to treat diastolic dysfunction in HFpEF
KL Dominic, AV Schmidt, H Granzier… - Frontiers in …, 2024 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is a major public health challenge,
affecting millions worldwide and placing a significant burden on healthcare systems due to …
affecting millions worldwide and placing a significant burden on healthcare systems due to …
Cardiac Myosin-Binding Protein C N-Terminal Dynamics: Structural Insights from Time-Resolved Fluorescence Studies
RS Kanassatega - 2023 - search.proquest.com
Cardiac myosin-binding protein C (cMyBP-C) is a thick filament-associated sarcomeric
protein that modulates the strength and kinetics of cardiac muscle contraction and …
protein that modulates the strength and kinetics of cardiac muscle contraction and …
Cardiac Myosin-Binding Protein C N-Terminal Interactions with Myosin: Binding Insights from Fluorescence Lifetime Studies
FL Wong - 2024 - repository.arizona.edu
Cardiac myosin-binding protein C (cMyBP-C), a sarcomeric protein associated with the thick
filament in the C-zone, finely tunes contractility and relaxation of the heart through its …
filament in the C-zone, finely tunes contractility and relaxation of the heart through its …