Blood flow forces in shaping the vascular system: a focus on endothelial cell behavior

P Campinho, A Vilfan, J Vermot - Frontiers in physiology, 2020 - frontiersin.org
The endothelium is the cell monolayer that lines the interior of the blood vessels separating
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …

[PDF][PDF] Cell behaviors and dynamics during angiogenesis

C Betz, A Lenard, HG Belting, M Affolter - Development, 2016 - researchgate.net
Vascular networks are formed and maintained through a multitude of angiogenic processes,
such as sprouting, anastomosis and pruning. Only recently has it become possible to study …

Coalescent angiogenesis—evidence for a novel concept of vascular network maturation

B Nitzsche, WW Rong, A Goede, B Hoffmann, F Scarpa… - Angiogenesis, 2022 - Springer
Angiogenesis describes the formation of new blood vessels from pre-existing vascular
structures. While the most studied mode of angiogenesis is vascular sprouting, specific …

Microvascular experimentation in the chick chorioallantoic membrane as a model for screening angiogenic agents including from gene-modified cells

DC Kennedy, B Coen, AM Wheatley… - International journal of …, 2021 - mdpi.com
The chick chorioallantoic membrane (CAM) assay model of angiogenesis has been
highlighted as a relatively quick, low cost and effective model for the study of pro-angiogenic …

Remodeling of the microvasculature: may the blood flow be with you

R Santamaría, M González-Álvarez, R Delgado… - Frontiers in …, 2020 - frontiersin.org
The vasculature ensures optimal delivery of nutrients and oxygen throughout the body, and
to achieve this function it must continually adapt to varying tissue demands. Newly formed …

The role of vasculature and angiogenesis in respiratory diseases

M Ackermann, C Werlein, E Plucinski, S Leypold… - Angiogenesis, 2024 - Springer
In European countries, nearly 10% of all hospital admissions are related to respiratory
diseases, mainly chronic life-threatening diseases such as COPD, pulmonary hypertension …

Synergistic interaction of sprouting and intussusceptive angiogenesis during zebrafish caudal vein plexus development

S Karthik, T Djukic, JD Kim, B Zuber, A Makanya… - Scientific Reports, 2018 - nature.com
Intussusceptive angiogenesis (IA) is a complementary method to sprouting angiogenesis
(SA). The hallmark of IA is formation of trans-capillary tissue pillars, their fusion and …

Intussusceptive angiogenesis as a key therapeutic target for cancer therapy

S Saravanan, S Vimalraj, K Pavani, R Nikarika… - Life sciences, 2020 - Elsevier
Deregulation of angiogenesis is a key reason for tumor growth and progression. Several anti-
angiogenic drugs in clinical practice attempt to normalize abnormal tumor vasculature …

Biofabrication strategies for creating microvascular complexity

AM Clyne, S Swaminathan, AD Lantada - Biofabrication, 2019 - iopscience.iop.org
Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …

Cell contractility facilitates alignment of cells and tissues to static uniaxial stretch

EG Rens, RMH Merks - Biophysical journal, 2017 - cell.com
During animal development and homeostasis, the structure of tissues, including muscles,
blood vessels, and connective tissues, adapts to mechanical strains in the extracellular …