In the human body, billions of cells die by apoptosis every day. The subsequent clearance of
apoptotic cells by phagocytosis is normally efficient enough to prevent secondary necrosis …

Viruses are infectious entities that hijack host replication machineries to produce their
progeny, resulting, in most cases, in disease and, sometimes, in death in infected host …

The efficiency of central nervous system remyelination declines with age. This is in part due
to an age-associated decline in the phagocytic removal of myelin debris, which contains …

In healthy individuals, billions of cells die by apoptosis every day. Removal of the dead cells
by phagocytosis (a process called efferocytosis) must be efficient to prevent secondary …

Atherosclerosis, a disease process characterized by lipid accumulation and inflammation, is
the main cause of coronary heart disease (CHD) and myocardial infarction (MI) …

The transcription factor MafB is expressed by monocytes and macrophages. Efferocytosis
(apoptotic cell uptake) by macrophages is important for inhibiting the development of …

Apoptosis is an important component of normal tissue physiology, and the prompt removal of
apoptotic cells is equally essential to avoid the undesirable consequences of their …

Apoptotic cell clearance by macrophages is key for normal tissue development and
homeostasis. Nuclear receptors, such as peroxisome proliferator activated receptors …

The safe removal of apoptotic debris by macrophages—often referred to as efferocytosis—is
crucial for maintaining tissue integrity and preventing self-immunity or tissue damaging …

Background Neurodegeneration is considered the consequence of misfolded proteins'
deposition. Little is known about external environmental effects on the neurodegenerative …