The novel applications of the quantitative analysis of neutrophil cell surface FcγRI (CD64) to the diagnosis of infectious and inflammatory diseases

J Nuutila - Current opinion in infectious diseases, 2010 - journals.lww.com
The best clinical benefit from the quantitative analysis of FcγRI on neutrophils will be
obtained when it is used simultaneously with a reliable bacterial infection marker. DNA virus …

Can biomarkers improve the rational use of antibiotics?

PS Fontela, S O'Donnell… - Current opinion in …, 2018 - journals.lww.com
Evidence shows that the use of biomarkers, procalcitonin and CRP, can safely reduce
unnecessary antibiotic prescriptions in certain infectious syndromes. The clinical utility of …

Simultaneous quantitative analysis of FcγRI (CD64) expression on neutrophils and monocytes: a new, improved way to detect infections

J Nuutila, U Hohenthal, I Laitinen, P Kotilainen… - Journal of …, 2007 - Elsevier
We performed simultaneous quantitative flow cytometric analysis of neutrophil and
monocyte FcγRI (CD64) in 289 hospitalized febrile patients. Microbiological evaluation or …

Combination of biomarkers for the discrimination between bacterial and viral lower respiratory tract infections

J ten Oever, M Tromp, CP Bleeker-Rovers… - Journal of Infection, 2012 - Elsevier
OBJECTIVES: To investigate whether additional determinations of plasma
lipopolysaccharide binding protein (LBP), procalcitonin (PCT), interleukin-6 (IL-6), IL-18, or …

Neutrophil CD64 expression as a diagnostic marker of bacterial infection in febrile children presenting to a hospital emergency department

B Rudensky, G Sirota, M Erlichman… - Pediatric …, 2008 - journals.lww.com
Background: The expression of CD64 (Fcγ receptor) is increased in neutrophils from an
almost negligible value to a marked level in patients with bacterial infections. CD64 …

Salivary immunity in elderly individuals presented with Candida‐related denture stomatitis

TH Gasparoto, CR Sipert, CE de Oliveira… - …, 2012 - Wiley Online Library
doi: 10.1111/j. 1741‐2358.2011. 00476. x Salivary immunity in elderly individuals presented
with Candida‐related denture stomatitis Objectives: Elderly individuals with Candida‐related …

Detailed phenotyping reveals diverse and highly skewed neutrophil subsets in both the blood and airways during active tuberculosis infection

S Nhamoyebonde, M Chambers, L Ndlovu… - Frontiers in …, 2024 - frontiersin.org
Introduction Neutrophils play a complex and important role in the immunopathology of TB.
Data suggest they are protective during early infection but become a main driver of …

Use of complement regulators, CD35, CD46, CD55, and CD59, on leukocytes as markers for diagnosis of viral and bacterial infections

J Nuutila, P Jalava-Karvinen, U Hohenthal… - Human immunology, 2013 - Elsevier
Several complement regulatory proteins exist on self-cells to prevent damage by the serum
complement system. In the present study, we aimed to perform quantitative analysis of …

Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients …

S Mokuda, O Doi, K Takasugi - Modern rheumatology, 2012 - Taylor & Francis
Objectives The expression level of CD64 on neutrophils can be used to differentiate
between an infection and a disease flare in rheumatoid arthritis (RA) patients. However, the …

Simultaneous quantitative analysis of FcγRI (CD64) and CR1 (CD35) on neutrophils in distinguishing between bacterial infections, viral infections, and inflammatory …

P Jalava-Karvinen, U Hohenthal, I Laitinen… - Clinical …, 2009 - Elsevier
A flow cytometric quantitative analysis of receptors on neutrophils can be exploited in
distinguishing between inflammatory and infectious diseases. In this prospective …