Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

Pediatric low-grade glioma in the era of molecular diagnostics

S Ryall, U Tabori, C Hawkins - Acta neuropathologica communications, 2020 - Springer
Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist

C McNamara, K Mankad, S Thust, L Dixon… - Neuroradiology, 2022 - Springer
The fifth edition of the World Health Organization Classification of Tumours of the Central
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …

DNA methylation profiling as a model for discovery and precision diagnostics in neuro-oncology

D Pratt, F Sahm, K Aldape - Neuro-oncology, 2021 - academic.oup.com
Recent years have witnessed a shift to more objective and biologically-driven methods for
central nervous system (CNS) tumor classification. The 2016 world health organization …

A radiologist's guide to the 2021 WHO Central Nervous System Tumor Classification: part I—key concepts and the spectrum of diffuse gliomas

DR Johnson, C Giannini, RA Vaubel, JM Morris… - Radiology, 2022 - pubs.rsna.org
The fifth edition of the World Health Organization (WHO) classification of tumors of the
central nervous system, published in 2021, contains substantial updates in the classification …

The oncogenic fusion landscape in pediatric CNS neoplasms

M Roosen, Z Odé, J Bunt, M Kool - Acta Neuropathologica, 2022 - Springer
Pediatric neoplasms in the central nervous system (CNS) are the leading cause of cancer-
related deaths in children. Recent developments in molecular analyses have greatly …

Treatment of pediatric low-grade gliomas

SF Sait, AM Giantini-Larsen, KR Tringale… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review Pediatric low-grade gliomas and glioneuronal tumors (pLGG)
account for approximately 30% of pediatric CNS neoplasms, encompassing a …

MGMT Promoter Methylation as a Prognostic Factor in Primary Glioblastoma: A Single-Institution Observational Study

M Szylberg, P Sokal, P Śledzińska, M Bebyn… - Biomedicines, 2022 - mdpi.com
Glioblastoma is the most malignant central nervous system tumor, which represents 50% of
all glial tumors. The understanding of glioma genesis, prognostic evaluation, and treatment …

[HTML][HTML] 2021 updates to the World Health Organization classification of adult-type and pediatric-type diffuse gliomas: a clinical practice review

DL Thomas - Chinese clinical oncology, 2023 - cco.amegroups.org
In 2021, the World Health Organization (WHO) Classification of Tumors of the Central
Nervous System (CNS) underwent significant restructuring to incorporate additional …

The 2021 WHO Classification for Gliomas and Implications on Imaging Diagnosis: Part 2—Summary of Imaging Findings on Pediatric‐Type Diffuse High‐Grade …

YW Park, P Vollmuth, M Foltyn‐Dumitru… - Journal of Magnetic …, 2023 - Wiley Online Library
The fifth edition of the World Health Organization (WHO) classification of central nervous
system tumors published in 2021 advances the role of molecular diagnostics in the …