Regulation mechanisms of viral IRES-driven translation
Internal ribosome entry sites (IRESs) can be found in the mRNA of many viruses as well as
in cellular genes involved in the stress response, cell cycle, and apoptosis. IRES-mediated …
in cellular genes involved in the stress response, cell cycle, and apoptosis. IRES-mediated …
Picornavirus IRES elements: RNA structure and host protein interactions
E Martínez-Salas, R Francisco-Velilla… - Virus research, 2015 - Elsevier
Internal ribosome entry site (IRES) elements were discovered in picornaviruses. These
elements are cis-acting RNA sequences that adopt diverse three-dimensional structures and …
elements are cis-acting RNA sequences that adopt diverse three-dimensional structures and …
[HTML][HTML] Advances in anti-EV-A71 drug development research
Abstract Background Enterovirus A71 (EV-A71) is capable of causing hand, foot and mouth
disease (HFMD), which may lead to neurological sequelae and even death. As EV-A71 is …
disease (HFMD), which may lead to neurological sequelae and even death. As EV-A71 is …
Far upstream element binding protein 1: a commander of transcription, translation and beyond
J Zhang, QM Chen - Oncogene, 2013 - nature.com
The far upstream binding protein 1 (FBP1) was first identified as a DNA-binding protein that
regulates c-Myc gene transcription through binding to the far upstream element (FUSE) in …
regulates c-Myc gene transcription through binding to the far upstream element (FUSE) in …
The master regulator FUBP1: its emerging role in normal cell function and malignant development
L Debaize, MB Troadec - Cellular and Molecular Life Sciences, 2019 - Springer
Abstract The human Far Upstream Element (FUSE) Binding Protein 1 (FUBP1) is a
multifunctional DNA-and RNA-binding protein involved in diverse cellular processes. FUBP1 …
multifunctional DNA-and RNA-binding protein involved in diverse cellular processes. FUBP1 …
Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus
The compartmentalization of DNA replication and gene transcription in the nucleus and
protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus …
protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus …
Immunopathogenesis and virus–host interactions of enterovirus 71 in patients with hand, foot and mouth disease
Enterovirus 71 (EV71) is a global infectious disease that affects millions of people. The virus
is the main etiological agent for hand, foot, and mouth disease with outbreaks and …
is the main etiological agent for hand, foot, and mouth disease with outbreaks and …
Role of p38 mitogen‐activated protein kinase signalling in virus replication and potential for developing broad spectrum antiviral drugs
Mitogen‐activated protein kinases (MAPKs) play a key role in complex cellular processes
such as proliferation, development, differentiation, transformation and apoptosis. Mammals …
such as proliferation, development, differentiation, transformation and apoptosis. Mammals …
Molecular pathogenicity of enteroviruses causing neurological disease
A Majer, A McGreevy, TF Booth - Frontiers in microbiology, 2020 - frontiersin.org
Enteroviruses are single-stranded positive-sense RNA viruses that primarily cause self-
limiting gastrointestinal or respiratory illness. In some cases, these viruses can invade the …
limiting gastrointestinal or respiratory illness. In some cases, these viruses can invade the …