Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …

For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

The difficulty in delineating brain tumor margins is a major obstacle in the path toward better
outcomes for patients with brain tumors. Current imaging methods are often limited by …

Cancers are often impossible to visually distinguish from normal tissue. This is critical for
brain cancer where residual invasive cancer cells frequently remain after surgery, leading to …

This perspective presents recent developments in the application of surface-enhanced
Raman spectroscopy (SERS) to biosensing, with a focus on in vivo diagnostics. We describe …

Despite significant effort, cancer still remains a leading cause of death worldwide. In order to
reduce its burden, the development and improvement of noninvasive strategies for early …

The current difficulty in visualizing the true extent of malignant brain tumors during surgical
resection represents one of the major reasons for the poor prognosis of brain tumor patients …

There is an urgent need for improved techniques for disease detection. Optical spectroscopy
and imaging technologies have potential for non-or minimally-invasive use in a wide range …

Raman scattering has long been used to analyze chemical compositions in biological
systems. Owing to its high chemical specificity and noninvasive detection capability, Raman …

Simple Summary Raman Spectroscopy (RS) is an optical technique able to determine
biochemical differences within a biological tissue, yet there are few reports of its application …