We introduce causal interaction tree (CIT) algorithms for finding subgroups of individuals with heterogeneous treatment effects in observational data. The CIT algorithms are …
The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment …
The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment …
P Liu, Y Li, J Li - Biometrics, 2025 - academic.oup.com
Pharmacogenomics stands as a pivotal driver toward personalized medicine, aiming to optimize drug efficacy while minimizing adverse effects by uncovering the impact of genetic …
Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are increasingly used to compare marginal treatment effects when there are cross-trial …
Y Chen, VV Chirikov, XL Marston, J Yang… - Journal of Health …, 2020 - ncbi.nlm.nih.gov
Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization …
Health technology assessment systems base their decision-making on health-economic evaluations. These require accurate relative treatment effect estimates for specific patient …
A key objective in an interventional study, such as a randomised clinical trial, is the evaluation of heterogeneity of treatment effect in the population. This allows us to identify the …
In medical studies, there is a growing interest in unraveling how the impact of a treatment varies in relation to an individual's observed covariates. The past decade has witnessed a …