Addressing systematic missing data in the context of causally interpretable meta-analysis

DH Barker, R Bie, JA Steingrimsson - Prevention Science, 2023 - Springer
Evidence synthesis involves drawing conclusions from trial samples that may differ from the
target population of interest, and there is often heterogeneity among trials in sample …

Causal interaction trees: Finding subgroups with heterogeneous treatment effects in observational data

J Yang, IJ Dahabreh, JA Steingrimsson - Biometrics, 2022 - Wiley Online Library
We introduce causal interaction tree (CIT) algorithms for finding subgroups of individuals
with heterogeneous treatment effects in observational data. The CIT algorithms are …

Tree-based subgroup discovery using electronic health record data: heterogeneity of treatment effects for DTG-containing therapies

J Yang, AW Mwangi, R Kantor, IJ Dahabreh… - …, 2024 - academic.oup.com
The rich longitudinal individual level data available from electronic health records (EHRs)
can be used to examine treatment effect heterogeneity. However, estimating treatment …

Tree-based subgroup discovery in electronic health records: Heterogeneity of treatment effects for dtg-containing therapies

J Yang, AW Mwangi, R Kantor, IJ Dahabreh… - arXiv preprint arXiv …, 2022 - arxiv.org
The rich longitudinal individual level data available from electronic health records (EHRs)
can be used to examine treatment effect heterogeneity. However, estimating treatment …

Change surface regression for nonlinear subgroup identification with application to warfarin pharmacogenomics data

P Liu, Y Li, J Li - Biometrics, 2025 - academic.oup.com
Pharmacogenomics stands as a pivotal driver toward personalized medicine, aiming to
optimize drug efficacy while minimizing adverse effects by uncovering the impact of genetic …

Marginalization of regression-adjusted treatment effects in indirect comparisons with limited patient-level data

A Remiro-Azócar, A Heath, G Baio - arXiv preprint arXiv:2008.05951, 2020 - arxiv.org
Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are
increasingly used to compare marginal treatment effects when there are cross-trial …

[HTML][HTML] Machine learning for precision health economics and outcomes research (P-HEOR): conceptual review of applications and next steps

Y Chen, VV Chirikov, XL Marston, J Yang… - Journal of Health …, 2020 - ncbi.nlm.nih.gov
Precision health economics and outcomes research (P-HEOR) integrates economic and
clinical value assessment by explicitly discovering distinct clinical and health care utilization …

Population-adjusted indirect treatment comparisons with limited access to patient-level data

A Remiro Azócar - 2022 - discovery.ucl.ac.uk
Health technology assessment systems base their decision-making on health-economic
evaluations. These require accurate relative treatment effect estimates for specific patient …

[图书][B] Assessing treatment effect heterogeneity: predictive covariate selection and subgroup identification

K Papangelou - 2021 - search.proquest.com
A key objective in an interventional study, such as a randomised clinical trial, is the
evaluation of heterogeneity of treatment effect in the population. This allows us to identify the …

On Subgroup Identification Via Change Point Detection and Model Average

L Pan - 2023 - search.proquest.com
In medical studies, there is a growing interest in unraveling how the impact of a treatment
varies in relation to an individual's observed covariates. The past decade has witnessed a …