Objective: There is burgeoning interest in augmentation strategies for improving inadequate
response to antidepressants. The adjunctive use of standardized pharmaceutical-grade …

Background Depression is a recurrent illness with high rates of chronicity, treatment‐
resistance and significant economic impact. There is evidence in the literature that S …

Objective Diet is increasingly recognized as a potentially modifiable factor influencing the
onset and outcomes of psychiatric disorders. Whereas, previous research has shown long …

Background One of the most pressing questions in “Nutritional Psychiatry” is whether using
combinations of different nutraceuticals with putative antidepressant activity may provide an …

Given the moderate efficacy of the currently available antidepressants (ADs) in the treatment
of major depressive disorder (MDD), the identification of agents that are both able to …

There has been increasing interest in nutraceutical augmentation strategies to boost the
efficacy of antidepressants. This study assessed whether S-adenosylmethionine (SAMe), a …

Purpose Depression clinical trials are increasingly studying biomarkers to predict and
monitor response to treatment. Assessment of biomarkers may reveal subsets of patients …

Objectives: The aim of this paper is to detail a summary of the current evidence in this area,
to better inform clinical practice. Our recent systematic reviews and meta-analyses of nutrient …

Background Diet has been associated with better mental health in general populations, but
less is known on this association in patients with a history of coronary heart disease. The …

Aim The effects of nutrient‐based treatments, including adjunctive vitamin or antioxidant
supplementation, have been explored extensively in long‐term schizophrenia. However, no …